Location & dates EMBL Heidelberg, Germany 15 - 20 Oct 2017
Deadlines Application closed
organiser_EMBO_Course_2017

EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.


Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Programme

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Day 1 - Sunday 15 October 2017
TimeSpeaker
12.00 Arrival and check-in B&B Hotel
13.45 - 14.00 Bus from B&B Hotel to Heidelberg City Tour
14.00 - 16.00 Heidelberg city excursion for speakers and participants
16.00 - 16:30 Bus from Neckarmunzplatz to EMBL
16.30 - 17.00

Registration

17.00 - 18.00

Welcome and introduction to the meeting
Rules and regulations for the ATC
Jacqueline Dreyer-Lamm- EMBL Heidelberg, Germany
Highlights and perspectives of humanized mice 

Leonard Shultz - The Jackson Laboratory, USA

18.00 - 20.00

Moderating participants and speakers for introductions
Renata Stripecke- Hannover Medical School, Germany

20.00 Dinner
Day 2 - Monday 16 October 2017
TimeSpeaker
08.30 – 09.15

New strains of mice for humanization
Michael Brehm- University of Massachusetts Medical School, USA

09.15 - 10.00

Human HSC engraftment in Kit-mutant recipient mice
Claudia Waskow- Technische Universität Dresden, Germany

10.00- 10.30 Coffee break
10.30 – 11.15

Development of innate and adaptive responses
James di Santo- Institut Pasteur, France

11.15 - 12.00

Adoptive DCs, adaptive immune response and CMV infection
Renata Stripecke- Hannover Medical School, Germany

12.00 - 12.45

Long term immune reconstitution in humanized mice
Roberto Speck- Universtiy Hospital Zürich, Switzerland

12.45 - 13.45 Lunch break
14.00 - 14.45

DC and NK innate immune responses and EBV infection
Christian Muenz - University of Zurich, Switzerland

14.45 - 15.30

Investigating antibody-mediated therapies in HIV-1-infected humanized mice
Florian Klein- University of Cologne, Germany

15.30 - 16.00

Coffee break

16.00 - 16.45

Liver-immune system and innate immune responses HBV and HCV
Marcus Dorner - Imperial College London, UK

16.45 - 17.45

Adenovirus, Ebola and Merkel Cell Polyoma infections
Estefania Rodriguez-Burgos - Heinrich Pette Institute Hamburg, Germany

18.00 - 19.00

Dinner

19.00 - 21.00

Poster Session (even numbers) & Drinks

Day 3 - Tuesday 17 October 2017
TimeSpeaker
09.00 - 12.30

Practical Class 1:
Selection of human hematopoietic stem cells, T cells,
monocytes for humanization and post transplantation analyses of immune reconstitutions
Renata Stripecke -Hannover Medical School, Germany
Michael Brehm -University of Massachusetts Medical School, USA
Claudia Waskow -Technische Universität Dresden, Germany
Roberto Speck -Universtiy Hospital Zürich, Switzerland
James Di Santo -Institut Pasteur, France 
Sebastian Theobald -Hannover Medical School, Germany

12.30 - 13.30

Lunch

13.30 - 18.00

Practical Class 2:
Analyses of human infections in mice 

Christian Muenz - University of Zurich, Switzerland
Chun Yu - The Jackson Laboratory, USA
Florian Klein - Centre for Molecular Medicine Cologne, Germany
Marcus Dorner - Imperial College London, UK
Estefania Rodriguez - Heinrich Pette Institute Hamburg, Germany

18.00 - 19.00 General Discussion of Results and Troubleshooting
19.00 - 20.00

Dinner

20.00 - 22.00

Poster Session (odd numbers) & Drinks

Day 4 - Wednesday 18 October 2017
TimeSpeaker
09.00 - 09.45

Ossicle implants for engraftment of hematopoietic stem cells and leukemia
J.J. Schuringa - University of Groningen, The Netherlands

09.45 - 10.30

Cytokine KI mice and their use in engrafting human myeloid malignancies 
Alexandre Theocharides - Universtiy Hospital Zürich, Switzerland

10.30 - 11.00

Coffee break

11.00 - 11.45 DX models as tools to identify and target therapy resistance mechanism
in human pancreatic cancer
Andreas Trumpp - DKFZ ,Heidelberg, Germany
11.45 - 12.30 PDX: Melanoma
Chun Yu - The Jackson Laboratory, USA
12.30 - 13.45

Lunch

14.00 - 18.00

Practical Class 3: Biopsy collections and analyses of human malignancies in mice 
J.J. Schuringa -University of Groningen, The Netherlands
Alexandre Theocharides - Universtiy Hospital Zürich, Switzerland
Anja Wege - University Medical Center Regensburg, Germany
James Keck - The Jackson Laboratory, USA
Andreas Trumpp - DKFZ – Heidelberg, Germany
Lisa Becker - DKFZ- Heidelberg, Germany
Corinna Klein - HI-STEM, Germany
Beat Bornhauser - University of Zurich, Switzerland

18.00 - 19.00 General Discussion of Results and Troubleshooting
19.00 - 20.00

Dinner

20.00 - 20.45

PDX models combined with human immune system
James Keck - The Jackson Laboratory, USA

20.45 - 21.45

Evaluation of immune related therapeutic strategies for breast cancer in Humanized Tumor Mice (HTM)
Anja Wege -University Medical Center Regensburg, Germany

Day 5 - Thursday 19 October 2017
TimeSpeaker
09.00 - 09.45

Applications of human liver chimeric mice in biomedical science
Karl-Dimiter Bissig - Baylor College of Medicine, USA

09.45 - 10.30

Molecular regulators of liver regeneration
Amar Sharma - Hannover Medical School, Germany

10.30 - 11.00

Coffee break

11.00 - 11.45

In vitro expansion of human cells for generation of xenograft infection models
Dagmar Wirth- Helmholtz Centre for Infection Research, Germany

11.45 - 12.30

Testing monoclonal antibodies against cancer
Johannes Sam- Roche Zurich, Switzerland

12.30 - 13.45 Lunch
13.45 - 18.00

Practical Class 4: Regenerative Medicine
Karl -Dimiter Bissig - Baylor College of Medicine, USA
Amar Sharma - Hannover, Germany
Dagmar Wirth -Helmholtz Centre for Infection Research, Germany
Johannes Sam - Roche Zurich, Switzerland

18.00

Dinner Downtown  

Day 6 - Friday 20 October 2017
TimeSpeaker
09.00 - 09.45

Genetic analyses and profiling of ALL
Jean Pierre Bourquin- University of Zurich, Switzerland

09.45 - 10.30

Muscle development, disease and repair
Nadia Rosenthal- The Jackson Laboratory, USA

10.30 - 11.00 Coffee break
11.00 -11.30

Immune response to vaccines, biotherapeutic medicines
and stem cells with a regulatory perspective

Sandrine Vessillier- Biotherapeutics NIBSC, UK

11.30 - 12.00

Drug Safety and Efficacy Testing in BLT Humanized Mice
Kristina Howard - Food and Drug Administration, USA

12.00 - 13:15

Lunch

13:15 - 15:00

Discussions, closing remarks and departure