Location & dates EMBL Heidelberg, Germany 23 - 25 May 2018
Deadlines Registration closed Abstract submission closed

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Day 1 - Wednesday 23 May 2018
09:30-11:00 Registration
11:00-11:15 Welcome and Introduction

Scientific Session 1: Vector biology and Transmission
Session Chairs: Elena Levashina, Martin Rono


Keynote Lecture 
On sporozoite formation, motility and attenuation
Freddy Frischknecht - Heidelberg University Hospital, Germany


Attach and infect – Identification of a mosquito receptor for the Plasmodium ookinete
Florian Brod - Oxford University, United Kingdom

12:00-12:15 Elucidating the role of lipolytic pathway in mosquito reproduction and P. falciparum transmission
Maurice Itoe - Harvard T.H. Chan School of Public Health, United States of America
12:15-12:30 Lipid requirements for life-cycle transition of the malaria parasite
Alexander G. Maier - The Australian National University Canberra, Australia
12:30-13:30 Lunch and meet the Keynote speaker
13:30-16:00 Scientific Session 2: Omics and Systems biology
Session Chairs: Richard Bartfai, Rita Tewari
13:30-14:00 Keynote Lecture
Finding function in parasite and vector population genomic variation
Daniel Neafsey - Broad Institute, United States of America
14:00-14:15 Integrated parasite load and dual transcriptome analysis of systemic host-parasite interactions in severe malaria
Aubrey Cunnington - Imperial College London, Australia        

The Malaria Cell Atlas
Andrew Russell - Wellcome Trust Sanger Institute, United Kingdom


Identifying localisation at scale with a novel platform for high-throughput automated Plasmodium culture
Theo Sanderson - Wellcome Trust Sanger Institute, United Kingdom


Global mapping of protein subcellular location in apicomplexans: the parasite as we've never seen it before
Ross Waller - University of Cambridge, United Kingdom

15:00-15:30 Flash Talks - Abstracts #48 Ellen Bushell, #50 Manuela Carasquilla, #76 Sebastian Kirchner, #102 David Oyen, #120 Lilach Scheiner, #126 Timothy Straub, #142 Danny Wilson, #35 Yaw Bediako, #45 Nicolas Blanchard, #53 Romain Coppée
15:30-16:00 Coffee Break and meet the Keynote speaker
16:00-18:00 Poster Session 1 - Even Numbers
18:00-18:45 Lifetime Achievement Award
18:45-20:30 Dinner
20:30-23:00 Welcome Reception

Day 2 - Thursday 24 May 2018
09:00-10:30 Scientific Session 3: Molecular and Cellular Biology (1)
Session Chairs: Lilach Sheiner, Sebastian Kirchner
09:00-09:30 Keynote Lecture
Cryptosporidium? Think Intestinal Malaria!
Boris Striepen - University of Pennsylvania, United States of America

Control of the Nedd8 pathway in Plasmodium falciparum
Katerina Artavanis-Tsakonas - University of Cambridge, United Kingdom


Push and Pull: F-actin facilitates Apicomplexan parasite penetration by forming an F-actin ring structure close to the tight junction
Mario Del Rosario - University of Glasgow, United Kingdom


RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics
Catherine Merrick - Keele University, United Kingdom


Uncovering the function of EXP1 in P. falciparum blood stages
Paolo Mesen-Ramirez - Bernhard Nocht Institute for Tropical Medicine, Germany          

10:30-11:00 Coffee Break and meet the Keynote speaker
11:00-12:30 Scientific Session 4: Host-Parasite interactions
Session Chairs: Petra Rohrbach, Marta Tiburcio
11:00-11:30 Keynote Lecture
Antigenic Variation in T.brucei: A Host-Pathogen Interaction Reduced to First Principles
Nina Papavasiliou - German Cancer Research Center (DKFZ), Germany

Combining RNA-sequencing and mathematical modelling to identify mechanistic correlates of protection in malaria
Athina Georgiadou - Imperial College London, United Kingdom

11:45-12:00 Impact of malaria-protective glycophorin polymorphism on Plasmodium falciparum invasion
Silvia Kariuki - KEMRI Wellcome Trust Research Programme, Kenya
12:00-12:15 The trophoblast endothelin response as a mechanism for fetal protection in placental malaria
Yash Pandya - Instituto Gulbenkian de Ciência, Portugal
12:15-12:30 Microvesicles from Malaria-infected Red Blood Cells Activate Natural Killer Cells via MDA5 Pathway
Peter Preiser - Nanyang Technological University, Singapore               
12:30-14:00 Lunch and meet the Keynote speaker
13:00-14:00 Workshop: Life beyond the P value - from elementary to advanced data analysis
Moderator: Mario Recker - University of Exeter, United Kingdom
13:00-14:00 Workshop: Make up your parasites with CRISPR/Cas9
Moderators: Marcus Lee - Wellcome Trust Sanger Institute, United Kingdom
Scott Lindner - Center for Malaria Research, Pennsylvania State University, United States of America 
14:00-16:00 Scientific Session 5: Immunobiology and Vaccine development
Session Chairs: Nicolas Blanchard, David Oyen
14:00-14:30 Keynote Lecture
The HIV Vaccine Problem
Michel Nussenzweig - The Rockefeller University, United States of America
14:30-14:45 Neutrophil proteases regulate malaria pathology by modulating inflammation and cytoadhesion
Borko Amulic - University of Bristol, United Kingdom
14:45-15:00 Clonal selection of potent germline antibodies drives protective memory B cell response in controlled human malaria infection
Rajagopal Murugan - German Cancer Research Center, Germany
15:00-15:15 Gametocyte immunity provides a rationale for novel transmission blocking interventions in Plasmodium falciparum
Priscilla Ngotho - University of Glasgow, United Kingdom
15:15-15:30 Evaluation of Plasmodium falciparum SPECT-1 as a novel pre-erythrocytic vaccine candidate
Ahmed Salman - Jenner Institute - University of Oxford, United Kingdom    
15:30-16:00 Flash Talks - Abstracts #57 Katrien Deroost, #61 Richard Bartfai, #65 José Luis Ruiz Rodriguez, #73 Ernst Joschner, #75 Che Julius Ngwa, #89 Oliver Lyth, #109Kimberley Prior, #113 Martin Rono, #117 Margarida Sanches-Vaz, #141 Mark Dale Wilkinson
16:00-16:30 Coffee Break and meet the Keynote speaker
16:30-18:30 Poster Session 2 - Odd Numbers
18:30-20:00 Conference Dinner
20:00-00:00 Conference Party 

Day 3 - Friday 25 May 2018
09:00-10:30 Scientific Session 6: Drugs and resistance
Session Chairs: Catherine Lavazec, Angelika Sturm

Keynote Lecture 
Mitochondrial heteroplasmy and atovaquone resistance in Plasmodium falciparum

Dennis Kyle - University of Georgia, United States of America


A genetic resistance trap in malaria parasites: exploiting the differential metabolism of the parasite between its two hosts
Hayley Buchanan - University of Melbourne, Australia


Unravelling the mode of action of a novel class of antimalarials
Laura E. de Vries - Radboud University Medical Centre, The Netherlands


Mind the Traffic: A role for trafficking in the ER stress response and artemisinin resistance in P. falciparum
Ryan Henrici - London School of Hygiene & Tropical Medicine, United Kingdom


Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine
Leila Ross - Columbia University, United States of America

10:30-11:00 Coffee Break and meet the Keynote speaker

Scientific Session 7: Molecular and Cellular Biology (2)
Session Chairs: Taco Kooij, Carolina Agop Nersesian

11:00-11:30 Keynote Lecture
The complexity and the simplicity of host-Plasmodium interactions
Maria Mota - Instituto de Medicina Molecular, Portugal
11:30-11:45 An enzyme pathway regulates malaria parasite egress
Michael Blackman - The Francis Crick Institute, United Kingdom

Genetic interactions reveal functional redundancy between calcium-dependent protein kinases 4 and 1 in motility and invasion of malaria parasites
Hanwei Fang - University of Geneva, Switzerland  

12:00-12:15 A high-throughput liver stage phenotyping screen of P. berghei knockouts reveals novel insights into Plasmodium metabolism
Rebecca Limenitakis Stanway - University of Bern, Switzerland
12:15-12:30 CAF1/CCR4/NOT Proteins Crucially Regulate Gametocyte Development and Transmissibility
Scott Lindner - Center for Malaria Research, Pennsylvania State University, United States of America
12:30-14:30 Lunch and meet the Keynote speaker
13:00-14:30 Panel Discussion: Career development - science and more
Moderators: Peter Preiser - Nanyang Technological University, Singapore
                     Rachel Graf - EMBL Heidelberg, Germany
14:30-14:45 Awards for best Posters and Oral presentations
14:45-15:00 Closing remarks
15:00-15:15 Departure