Location & dates EMBL Heidelberg, Germany 17 - 20 Oct 2018
Deadlines Registration closed Abstract submission closed
organiser_EMBO_Workshop_2017

Programme

The final programme is available as a PDF here.

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Day 1 - Wednesday, 17 October 2018
TimeSpeaker
15:30-17:00 Registration 
  Session 1 -  Systems and Synthetic Biology
Chair: Peter Philippsen
17:00 – 17:15 Opening remarks
17:15 – 17:45

Writing genomes
Jef Boeke - New York University, USA

17:45 – 18:15

WHO's yo' Momma, HO?
Ken Wolfe - University College Dublin, Ireland

18:15 – 18:45
Epigenetic feedbacks linking DNA‑dependent processes:  how cells maintain expression homeostasis during DNA replication

Naama Barkai - Weizmann Institute of Science, Israel

18:45 – 19:05

Molecular drivers of complex heritability revealed by a natural genotype to phenotype map

Christopher M Jakobson, Stanford University School of Medicine, USA

19:05 – 19:25

Chemical genomics in genetically diverse strains of Saccharomyces cerevisiae

Bede Busby, EMBL Heidelberg, Germany

19:25 - 23:00

Dinner and get together

Day 2 - Thursday, 18 October 2018
TimeSpeaker
  Session 2 - Evolutionary Systems Biology I
Chair: Anja Forche
09:00-09:30

Can microbes help explain the evolution of host cooperation? 
Lilach Hadany - Tel Aviv University, Israel

09:30-10:00

Yeast as a model to understand how new genes are born
Anne-Ruxandra Carvunis - University of Pittsburgh, USA

10:00-10:20

Mapping genetic variation in gene expression by simultaneous quantification of mRNA and protein levels in single cells

Christian Brion, University of Minnesota, USA

10:20-10:50

Coffee Break

10:50-11:20

Paralogous interference in cellular networks
Christian Landry - Université Laval, Canada

11:20-11:50

Division of labour: laboratory evolution of a synthetic consortium of Saccharomyces cerevisiae strains for second generation bioethanol production
Maarten Verhoeven - DSM, The Netherlands

11:50-12:10

Recombining your way out of trouble: Adaptation to stressful environments through hybridization

Rike Stelkens, Stockholm University, Sweden

12:10-12:30

Dramatic variations in extrachromosomal DNA circle complement are caused by environmentally responsive gene expression

Jonathan Houseley, Babraham Institute, UK

12:30-13:30

Lunch

13:30-14:10

Poster Introduction (odd numbers)

14:10-16:00

Poster Session I (odd numbers)

Session 3. Experimental Evolution
Chair: Jolanda van Leeuwen

16:00 -16:30

The complex underpinnings of genetic background effects

Ian Ehrenreich  - University of Southern California, USA

16:30-17:00

The shape of adaptation and trade-offs

Gavin Sherlock - Stanford University, USA

17:00-17:20

Re-coding the Saccharomyces cerevisiae genome through evolution

Ana Rita Guimarães, University of Aveiro, Portugal

17:20-17:50

Coffee Break

17:50-18:20

A renewable barcoding system for high-resolution lineage tracking in laboratory yeast

Michael Desai - Harvard University, USA

18:20-18:50

Systems biology of yeast metabolism
Jens Nielsen - Chalmers University of Technology, Sweden

18:50-19:10

Repurposing the function of a kleisin protein in budding yeast

Yu Ying Phoebe Hsieh, Harvard University, USA

19:20-21:30

Dinner

21:30-24:00

After Dinner Drinks

Day 3 - Friday 19 October 2018
TimeSpeaker
  Session 4 - Metabolic and Inter-species Networks I

Chair: Frank Albert

09:00-09:30 Nematode pheromone mediated prey sensing is highly polymorphic among the wild isolates of nematode trapping fungi
Yen-Ping Hsueh - Academia Sinica, Taiwan
09:30-10:00

Rapid adaptation to the host environment by Cryptococcus neoformans involves genomic changes
Kirsten Nielsen - University of Minnesota, USA

10:00-10:20

Comparative pangenome analysis across yeast species reveals a variability shaped by introgression events

Anne Friedrich, University of Strasbourg / CNRS, France

10:20-10:50

Coffee break 

10:50-11:20

Talk title to be announced
Markus Ralser - University of Cambridge, UK

11:20-11:50

Unravelling inter species metabolite exchange by combining modeling, genetic and metabolomic approaches
Kiran Patil - EMBL Heidelberg, Germany

11:50-12:10

Induction of aneuploidy enables yeast to grow without the major membrane lipid phosphatidylcholine

Xue Bao, Utrecht University, The Netherlands

12:10-12:30

The landscape of S. paradoxus introgression in S. cerevisiae strains from diverse environments

Anne Clark, University of Washington, USA

12:30-13:30 Lunch 
13:30-14:10 Poster Introduction  (even numbers)
14:10-16:00 Poster Session II (even numbers)
Free evening
17:00-18:30 Optional: Brewery Tour to Brauerei zum Klosterhof (additional costs may apply, limited spaces)
Day 4 - Saturday 20 October 2018
TimeSpeaker
 

Session 5. Evolutionary Systems Biology II
Chair: Shay Ben Aroya

09:00-09:30

Proteotoxic stress due to loss of interaction partners induces reproductive isolation in yeast hybrids
Jun-Yi Leu - Academia Sinica, Institute of Molecular Biology, Taipei

09:30-10:00

Feedbacks on cyclin dependent kinase activity: evolution of safety nets for cell cycle control
Damien Coudreuse- Institute of Genetics & Development of Rennes, France

10:00-10:20

Compensated deleterious mutations as drivers of morphological evolution

Balazs Papp, Biological Research Centre of the Hungarian Academy of Sciences, Hungary

10:20-10:50 Coffee break
10:50-11:20

Mechanisms controlling variation in yeast growth
Mark Siegal  - New York University, USA

11:20-11:50

Genetic assimilation of epigenetic adaptation in experimental yeast populations

Jonas Warringer - University of Gothenburg, Sweden

11:50-12:10

Interactions between two transcription factors modulate positive feedback in a eukaryotic bistable system

Naomi Ziv, University of California, San Francisco, USA

12:10-12:30

Host virus coevolution in laboratory populations of yeast

Sean Buskirk, Lehigh University, USA

12:30-14:00 Lunch

Session 6. Evolution of complex traits I
Chair: Giulia Rancati

14:00-14:30 Evolving cross resistance via aneuploidy in Candida albicans
Judith Berman - Tel Aviv University, Israel
14:30-15:00

Natural variation in the response to gene over expression in wild Saccharomyces cerevisiae strains

Audrey Gasch, University of Wisconsin Madison, USA

15:00-15:20

Single cell copy number variant detection reveals the dynamics and diversity of adaptation

David Gresham, New York University

15:20-15:50 Coffee Break 

Session 7. Metabolic and Inter-species Networks II
Chair: Hsin Hung Chou TBA

15:50-16:20

Genetic conflicts and developmental constraints shape centromeric histone function

Harmit Malik  - Fred Hutchinson Cancer Research Center, USA

16:20-16:50

Evolution of functional promoters from random sequences

Jeff Gore, Massachusetts Institute of Technology, USA

16:50-17:10

Genetic dissection of an ancient divergence in yeast thermotolerance

Rachel Brem, University of California, Berkeley, USA

17:10 – 17:40 Coffee Break 

Session 8. Evolution of complex traits II

Chair: Gianni Liti

17:40-18:10

Surrogate Genetics: Science at the interface of precision medicine and synthetic biology

Aimee Dudley  - Pacific Northwest Research Institute, USA

18:10:18:40

Gain of function mutations in yeast evolved in and out of the lab
Maitreya Dunham - University of Washington, USA

18:40-19:00

High resolution yeast meiotic recombination landscape and its genomic modulators

Jia Xing Yue, Université Côte d'Azur, CNRS, Inserm, IRCAN, France

19:00-20:30 Dinner 
20:30-24:00 Party