Location & dates EMBL Heidelberg, Germany 25 - 27 Apr 2018
Deadlines Registration closed Abstract submission closed

Programme

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Day 1 - Wednesday 25 April 2018
TimeSpeaker
12.00 - 13.20

Registration
Welcome coffee & light snacks

13.20 - 13.30 Opening remarks
13.30 - 17:30

Session 1: 3' Non-templated nucleotide additions

13.30 - 14.00

Tailing in the regulation of mRNAs and small noncoding RNAs
Narry Kim - Seoul National University, Korea

14.00 - 14.15

On the optimal design of metabolic RNA labeling experiments
Alexey Uvarovskii - University Hospital Heidelberg, Germany

14.15 - 14.45

RNAi and selective sequence-independent translational repression induced by dsRNA in mammalian cells
Petr Svoboda - Institute of Molecular Genetics of the ASCR, v. v. i., Czech Republic

14.45 - 15.00

Initial poly(A) tail size is regulated during the serum response
Cornelia de Moor - University of Nottingham, UK

15.00 - 15.30

Coffee break

15.30 - 16:00

The role of the adenosine demethylase FTO in the mammalian nucleus
Štěpánka Vaňáčová - CEITEC , Masaryk University, Czech Republic

16.00 - 16.15

Organ-wide Profiling of Adenosine to Inosine RNA Editing of Filamin B in Mouse
Laura Cimatti - Medical University of Vienna, Austria

16.15 - 16.45

Deciphering a novel role of Adar in Drosophila development
Mary O'Connell - CEITEC, Czech Republic

16.45 - 17.00

A vastly increased chemical variety of RNA modifications that includes a thioacetal structure
Mark Helm - Johannes Gutenberg-University, Germany

17.00 - 17.30

RNA editing is important for worm development and regulates RNAi
Ayelet Lamm - TECHNION Israel Institute of Technology, Israel

17.30 - 18.00

Coffee break

18.00 - 19.00

Keynote Lecture:
Epitranscriptomics – from basic principles to cancer

Gidi Rechavi  - Tel Aviv University, Israel

19:00 - 19:20

Talk title tbc
Francois Fuks - ULB, Belgium

19.20 - 20.30

Dinner

20.30 - 23.00 Welcome reception
Day 2 - Thursday 26 April 2018
TimeSpeaker
9.00 - 13.00 Session 2: Direct RNA modification
9.00 - 9.30 Distribution and regulation of cytosine-5 RNA methylation
Frank Lyko - DKFZ, Germany
9.30 - 10.00

Queuine links translational control in eukaryotes to a micronutrient from bacteria
Ann Ehrenhofer-Murray - Humboldt University of Berlin, Germany

10.00 - 10.15

Role of N6-methyladenosine in the translation of circular RNAs in eukaryotes
Gaia Di Timoteo - Sapienza University of Rome, Italy

10.15 - 10.30

Mutations in (Cytosine-5) tRNA Methyltransferases Impact Mobile Element Expression and Genome Stability at Specific DNA Repeats
Matthias Schaefer - Medical University Vienna, Austria

10.30 - 11.15

Coffee break

11.15 - 11.45

RNA modifications as signals and tools
Alexandra Lusser - Medical University of Innsbruck, Austria

11.45 - 12.15

Mapping the functional pseudouridine  and m1A landscape in the mammalian transcriptome
Chengqi Yi - Peking University, China

12.15 - 12.30 m1a on mRNA: Rare, dynamic and potent
Schraga Schwartz - Weizmann Institute of Science, Israel
12.30 -13.00

Human RNA cap1 methyltransferase CMTr1 and its activity on RNAs with highly structured 5' termini
Janusz Bujnicki - International Institute of Molecular and Cell Biology, Poland

13.00 -14.30

Lunch & "Meet the Speaker Session I"

14.30 -18.00

Session 3: RNA binding proteins; readers and regulators of the transcriptome

14.30 - 15.00

Uridylation by TUT4/7 restricts retrotransposition of human LINE-1
Andrzej Dziembowski -  Polish Academy of Sciences, Poland

15.00 - 15.15

Writing and reading of 5-methylcytosine orchestrates non-coding Vault RNA processing into small regulatory RNAs to coordinate epidermal differentiation
Abdulrahim Sajini - Khalifa University, United Arab Emirates

15.15 - 15.45

Genetic Dissection of m6A RNA Methylation Role in Early Mammalian Development
Jacob Hanna - Weizmann Institute of Science, Israel

15.45 - 16.15

RNA demethylation mediated through FTO
Chuan He - University of Chicago, USA

16.15 - 16.45

Coffee break

16.45 - 17.15

RNA Methylation Code:Regulations and Mechanisms
Yungui Yang - Beijing Institute of Genomics, China

17.15 - 17.30 Identification of the Tudor domain Royal family as a reader family of m6A-modified RNA
Belinda Baquero - University of Leeds, UK
17.30 - 18.00 Acetylation of cytidine in messenger RNA promotes translation efficiency
Shalini Oberdoerffer - NIH National Cancer Institute, USA
18.00 - 19.30 Dinner
19.30 - 21.30 Poster Session I (Even numbers)
21:30 - 23:00 Drinks in the Roof Top Lounge
Day 3 - Friday 27 April 2018
TimeSpeaker
09:00 -13.00 Session 4. RNA modifications as regulators of protein translation
09.00 - 09.30

co-transcriptional N6- adenosine methylation impacts mRNA translation
Reuven Agami - Netherlands Cancer Institute, The Netherlands

09.30 - 09.45

Pseudouridylation of tRNA-derived fragments steers translational control and stem cell commitment
Nicola Guzzi - Lund University, Sweden

09.45 - 10.00

tRNA methylation and mitochondrial protein synthesis in skin cancer
Sylvain Delaunay - University of Cambridge, UK

10.00 - 10.30

tRNA methylation: A mechanism to regulate gene expression
Ya-Ming Hou - Thomas Jefferson University, USA

10.30 - 11.00

Coffee break

11.00 - 11.30

N6-Methyladenosine Guides mRNA Alternative Translation
Shu-Bing Qian - Cornell University, USA

11.30 - 11.45

Flacc/Zc3h13 is required for m6A methylation by stabilizing the interaction between Nito/Rbm15 and Fl(2)d/Wtap
Tina Lence - Institute of Molecular Biology, Germany

11.45 - 12.15

Translation regulation through wobble tRNA modification in cancer
Pierre Close - University of Liegé, Belgium

12.15 - 12.30

The YTH domain protein ECT2 from Arabidopsis thaliana is an m6A reader required for normal trichome branching and which function is regulated by phosphorylation
Cécile Bousquet-Antonelli - CNRS, France

12.30 - 13.00

The price of epitranscriptomics
Sebastian Leidel - MPI for Molecular Biomedicine, Germany

13.00 -14.30 Lunch & "Meet the Speaker Session II"
14.30 -17.30 Session 5. RNA modifications/modifiers in development and disease
14.30 - 14.45

A plant m6A-YTH module in developmental timing and morphogenesis
Peter Brodersen - University of Copenhagen, Denmark

14.45 - 15.15

m6A RNA methylation regulates neural development and neurological disorders
Yanhong Shi - City of Hope, USA

15.15 - 15.30

N6-methyladenosine RNA modification (m6A) regulates Drosophila melanogaster nervous system development via modulation of Fmr1 function
Alessandro Quattrone - Centre for Integrative Biology, University of Trento, Italy


15.30 - 16.00

How to be non-conventional: the roles of RNA modifications in gene expression 

Markus Bohnsack - University Medical Center Göttingen, Germany
16.00 - 16.30

Coffee break

16.30 - 16.45

Deciphering the role of mRNA methylation in Drosophila sex determination and the nervous system
Matthias Soller - University of Birmingham, UK

16.45 - 17.15

Terminal uridylyltransferases target RNA viruses as part of the innate immune system in animals
Eric Miska - Gurdon Institute, UK

17.15 - 17.30

Title tbc
Kamil Kranc - University of Edinburgh, United Kingdom

17.30 - 19.00

Poster Session II (Odd numbers)

19.00 - 21.00

Banquet Dinner

21.00 - 00.00 Conference Party