Location & dates EMBL Heidelberg, Germany 18 - 21 Mar 2018
Deadlines Registration closed Abstract submission closed
organiser_EMBO_Workshop_2017

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Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Programme

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Day 1 - Sunday 18 March 2018
TimeSpeaker
11.30 - 13.15 Registration and Lunch
13.15 - 13.30

Opening remarks

13.30 - 14.30

Keynote Lecture
Nature and nurture of microglia identity and function
Christopher K. Glass - University of California, San Diego, USA

Session 1: Ontogeny and Diversity
Chair: Amanda Sierra

14.30 - 15.00

Understand Microglia Ontogeny                                                                                                      Florent Ginhoux - Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore

15.00 - 15.30

Genetic analysis of glial development and function in zebrafish                                                    William S. Talbot - Stanford University, United States of America

15.30 - 16.00

Coffee Break and meet the speakers

16.00 - 16.30

Microglia state changes during development and disease
Beth Stevens - Boston Children's Hospital, United States of America

16.30 - 17.00

Regulation of Brain Macrophage Development
Melanie Greter - University of Zurich, Switzerland

17.00 - 17.15

A combination of ontogeny and CNS environment establishes microglial identity    
Chris Benett - Stanford University, United States of America

17.15 - 17.30

BM-derived parenchymal brain macrophages differ from microglia in transcriptome, epigenome and responsiveness to challenge    
Steffen Jung - Weizmann Institute of Science, Israel

17.30 - 17.45

Zebrafish adult, but not embryonic microglia derive from c-myb dependent hematopoietic progenitors    
Valerie Wittamer - Universite Libre de Bruxelles (ULB), Belgium

17.45 - 18.00

Microglia-myelinogenic and neuroprotective cells in the CNS
Agnieszka Wlodarczyk - Institute for Molecular Medicine, University of Southern Denmark, Denmark

18.00 Dinner - EMBL Canteen
19.30 Bus leaves for Walking Tour downtown Heidelberg
Bus leaves for conference bus stops
Day 2 - Monday 19 March 2018
TimeSpeaker
Session 2: Microglia Physiology
Chair: David Atwell
09.00 - 09.30

How do microglia and astrocytes coordinate synapse elimination during development?
Mariko Bennett - Stanford University, United States of America

09.30 - 09.45

Cerebellar microglia are dynamically unique and survey Purkinje neurons in vivo
Rianne Stowell - University of Rochester, United States of America

09.45 - 10.00

Defective cholesterol clearance limits remyelination in the aged central nervous system
Ludovico Cantuti-Castelvetri - German Center for Neurodegenerative Disease Research (DZNE), Germany

10.00 - 10.30

Microglial ITAM/ITIM-signaling receptors for maintenance of the immune homeostasis in the brain
Harald Neumann - University of Bonn, Germany

10.30 - 11.00

Coffee Break and meet the speakers

11.00 - 11.15

Inflammatory microglia mediate early synapse loss in multiple models of multiple sclerosis
Sebastian Werneburg - University of Massachusetts Medical School, United States of America

11.15 - 11.30 Deficiency of Progranulin (PGRN) results in accelerated prion diseases
Caihong Zhu - Institute of Neuropathology, Switzerland   
11.30 - 11.45 Neuroprotective microglia and neurotoxic monocytes in epilepsy
Long-Jun Wu - Mayo Clinic, United States of America
11.45 - 12.00

Catatonia - starting to understand mechanisms involving myelin
Hana Janova - Max Planck Institute of Experimental Medicine, Germany

12.00 - 13.30

Lunch - EMBL Foyer

12.30 - 13.30

Panel Discussion - Let's mingle with Industry, ATC Courtyard Room

Session 3: Microglia and the synapse
Chair: Marco Prinz

13.30 - 14.00

Formation of Cortical Local Circuits by Microglia in Development
Junichi Nabekura - National Institute for Physiological Sciences, Japan

14.00 - 14.30

Molecular dissection of activity-dependent microglial function within neural circuits                   Dorothy P. Schafer - University of Massachusetts Medical School, United States of America

14.30 - 15.00

Do microglia really eat synapses?                                                                                                  Cornelius Gross - EMBL Rome, Italy

15.00 - 15.30 Coffee Break and meet the speakers
15.30 - 16.00 Microglial cells regulate the functional maturation of cortical circuits during postnatal                          development
Etienne Audinat - University of Montpellier, France
16.00 - 16.15 Tau pathology induced synapse labeling by C1q leads to removal of synapses by microglia    
Borislav Dejanovic - Genentech, United States of America                                    
16.15 - 16.30 Brain hyperthermia activates microglia to engulf inhibitory synapses in epilepsy    
Ryuta Koyama - The University of Tokyo, Japan 
16.30 - 17.00 Flash Talks: #43 S. Acharjee, #61 C. Chhatbar, #87 J. Hua, #127 B. Pinto, #133 D. Ragozzino, #167 R. von Bernhardi, # 171 P. West, #173 Y. Xu
17.00 - 19.00 Poster Session 1 - Odd numbers, ATC Helix A
19.00 - 21.00 Dinner - EMBL Canteen
21.00 - 23.00 Get together with live music - ATC Rooftop Lounge
Day 3 - Tuesday 20 March 2018
TimeSpeaker
Session 4: Microglia and Other Cells
Chair: Staci Bilbo
09.00 - 09.30

Microglia and prenatal inflammation in the early wiring of cortical circuits                                    Sonia Garel - Institut de Biologie de l’ENS (IBENS), France

09.30 - 10.00

Towards a dynamic quantitative understanding of how microglia keep the brain clean            Francesca Peri - University of Zürich, Switzerland

10.00 - 10.30

Factors regulating the function of microglia
Marco Prinz - University of Freiburg, Germany

10.30 - 11.00

Coffee Break and meet the speakers

11.00 - 11.15

Peripheral macrophage control of microglia during CNS injury    
Andrew Greenhalgh - INRA, University of Bordeaux, France

11.15 - 11.30

Glioma-induced inhibition of caspase-3 in microglia promotes a tumor-supportive phenotype    
Bertrand Joseph - Karolinska Institutet, Sweden 

11.30 - 11.45 Tumor initiating cells induce Cxcr4 mediated infiltration of pro-tumoral macrophages into the brain
Dirk Sieger - University of Edinburgh, United Kingdom
11.45 - 12.00 Early Maternal Stress Alters Microglia Responsiveness to Activation and Impacts Striatal Circuit Function and Behaviors    
Lindsay Hayes - Johns Hopkins University, United States of America
12.00 - 13.30

Lunch - EMBL Foyer

12.30 - 14.30

Panel discussion - Meet the Editors, ATC Courtyard Room

Session 5: Neurodegeneration/Psychiatric Disorders
Chair: Sonia Garel

CANCELLED

Microglial Transcriptomes: Foundations for Progress
Richard Ransohoff - Third Rock Ventures, United States of America

14.00 - 14.30

Microglial elimination of dopamine receptors defines sex-specific nucleus accumbens development and social behavior during adolescence
Staci Bilbo - MassGeneral Hospital for Children, USA

14.30 - 15.00

Microglial phagocytosis: from neurogenesis to neurodegeneration                                              Amanda Sierra - Ikerbasque, Basque Foundation for Science, Spain  

15.00 - 15.30

Coffee Break and meet the speakers

15.30 - 15.45 A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease    
Elvira Mass - LIMES Institute, University of Bonn, Germany
15.45 - 16.00 Microglial memory of peripheral inflammation shapes neurological disease    
Jonas Neher - German Centre for Neurodegenerative Diseases (DZNE), Germany
16.00 - 16.15 Loss of microglial TDP-43 induces alteration in cytokine expression and loss of synapses, associated with motor deficits in mice    
Rosa C. Paolicelli - University of Zurich, Switzerland
16.15 - 16.30 Microglia drives sickness behavior and social behavior through Serotonin 2B receptors. Implication for susceptibility to depression?
Anne Roumier - Institut du Fer à Moulin, France
16.30 - 17.00 Flash Talks: #66 A. Denes, #74 R. Gaspar, #80 L. Herrgen, #98 H. Konttinen, #100 J. Kotah, #128 S. Garofalo, #140 J. Rosin, #162 M. Mizee
17.00 - 19.00 Poster Session 2 - Even numbers, ATC Helix A
19.00 - 21.00 Conference Dinner - EMBL Canteen
21.00 - 00.00 Conference Party - ATC Foyer
Day 4 - Wednesday 21 March 2018
TimeSpeaker
Session 6: New Ways to study Microglia
Chair: Cornelius Gross
09.00 - 09.30

Dish Microglia: Towards Synthetic Models of Human Neuro-Immune Interactions                          Julien Muffat - The Hospital for Sick Children, Canada

09.30 - 09.45

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures    
Christopher Bohlen - Genentech, United States of America

09.45 - 10.00

New tools to study microglial self-renewal, clonal expansion and network re-organization    
Tuan Leng Tay - University of Freiburg, Germany   

10.00 - 10.15

Modelling neurodegenerative disease in human iPSC microglia neuronal-co-culture systems    
Walther Hänseler - University of Zurich, Switzerland

10.15 - 10.45

Coffee Break and meet the speakers

10.45 - 11.15

Ben Barres Young Speaker Prize and Poster Prizes

11.15 - 12.15

Keynote Lecture
Microglial membrane control of motility, Ca2+ signalling, immune function and vascular function
David Attwell - University College London, United Kingdom

12.15 - 12.30 Closing Remarks
12.30 - 13.00 Packed Lunch and departure 
13.00 Departure
- Bus leaving to Frankfurt International Airport
- Separate bus leaving for downtown