
Programme
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Time | ||
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11:00 - 12:30 | Arrival and Registration |
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12:30 - 12:45 | Opening remarks | |
12:45 - 13:30 |
Keynote speaker: Protein-metabolite networks |
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13:30 - 17:00 |
Session 1: Structure to Function |
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13:30 - 14:00 | A network biology approach to novel therapeutic strategies Patrick Aloy, IRB Barcelona, Spain |
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14:00 - 14:30 |
Quantitative mapping of human protein-protein interactions in health and disease |
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14:30 - 15:00 |
Coffee Break & Meet the Invited Speakers: Anne-Claude Gavin, Patrick Aloy, Erich Wanker |
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15:00 - 15:30 |
Characterizing the human proteostasis network with quantitative proteomics approaches |
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15:30 - 16:00 |
Modeling peripheral protein-membrane interactions |
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16:00 - 16:15 |
Evolutionary dynamics of herpesvirus protein domains |
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16:15 - 16:30 |
Identifying Cancer Driver Genes from Enrichment of Somatic Nonsynonymous Mutations at Protein Interaction Interfaces |
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16:30 - 16:45 |
Towards a reference map of the human protein interactome |
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16:45- 17:00 |
Flash Talks |
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17:00 - 18:30 |
Poster Session (odd numbers) with beer and snacks |
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18:30 - 20:00 | Dinner in the Canteen |
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20:00 - 21:30 | After Dinner Drinks in the ATC Rooftop Lounge |
Time | ||
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08:15 - 09:00 |
Keynote: Rob Russell University of Heidelberg, Germany |
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09:00 - 12:00 | Session 2: Network to Phenotype Mapping Chair: Anne-Claude Gavin, EMBL Heidelberg |
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09:00 - 09:30 |
Using transcriptional networks to understand breast cancer risk |
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09:30 - 10:00 |
Modelling cell cell interaction networks in muscle regeneration |
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10:00 - 10:30 |
Talk title to be announced |
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10:30 - 11:15 | Coffee Break & Meet the Invited Speakers: Mikko Taipale, Nathalie Reuter, Rob Russell, Kerstin Meyer, Gianni Cesareni |
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11:15 - 11:30 |
S2B (Double Specific Betweenness): a novel cross-disease network analysis method applied to motor neuron degeneration |
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11:30 - 11:45 | From network to phenotype: understanding the wiring of a stress-induced transcriptional network in Arabidopsis. Lisa Van den Broeck, VIB-PSB, Belgium |
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11:45 - 12:00 | Systems pharmacology dissection of cell-specific cholesterol regulation mechanisms reveals large pharmacodynamic variability Peter Blattmann, ETH Zurich, Switzerland |
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12:00 - 13:30 |
Lunch in the ATC Foyer |
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13:30 - 17:30 | Session 3: Network Dynamics & Modelling Chair: Sorina C. Popescu, Mississippi State University |
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13:30 - 14:00 |
From networks-based integration of omics data to dynamic logic models for improving cancer treatment |
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14:00 - 14:30 |
Phosphoproteomics data derived context specific signalling networks |
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14:30 - 15:00 |
Phenotyping Single Cell Derived Tumor Spheroids by Time Resolved Imaging |
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15:00 - 15:30 | Coffee Break & Meet the Invited Speakers: Julio Saez-Rodriguez, Evangelia Petsalaki, Roland Eils |
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15:30 - 16:00 | Executable Cell Biology: From Mechanistic Insights to New Avenues for Cancer Therapy Jasmin Fisher, University of Cambridge, United Kingdom |
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16:00 - 16:30 |
Mapping DNA damage-dependent protein interactions via conditional Barcode Fusion Genetics‐Yeast Two‐Hybrid |
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16:30- 16:45 |
From networks to mechanisms: A dynamic and functional characterization of the cell polarity interaction network in yeast |
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16:45 - 17:00 |
Time-resolved Global and Chromatin Proteomics during Herpes Simplex Virus (HSV-1) Infection |
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17:00 - 17:15 |
Adaptive rewiring of protein-protein interactions and signal flow in the EGFR signaling network by mutant RAS |
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17:15 - 17:30 |
Flash Talks |
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17:30 - 19:00 | Poster Session (even numbers) with beer and snacks | |
19:00 - 21:00 | Conference dinner in the Canteen | |
21:00 - 00:00 | Party in the ATC Foyer |
Time | ||
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08:15 -09:00 |
Career Workshop |
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09:00-19:00 |
Session 4: Integrative Network Approaches |
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09:00 - 09:30 | Applications of the Mammalian Membrane Two-Hybrid (MaMTH) Assay for Identification of Novel Cancer Targets & Therapeutics Igor Stagljar, University of Toronto, Donnelly Centre, Canada |
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09:30 - 10:00 |
Transcription networks regulating cardiac development and triggering cardiac diseases and function |
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10:00 - 10:30 | Molecular determinants of dominant negative mutations in protein complexes Joseph Marsh, University of Edinburgh, United Kingdom |
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10:30 - 11:00 | Coffee Break & Meet the Invited Speakers: Jasmin Fisher, Dae-Kyum Kim, Igor Stagljar, Silke Sperling, Joseph Marsh |
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11:00 - 11:15 |
Learning and Memory in Intra-Cellular Signaling Network : The Role of the MAPK Cascade |
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11:15 - 11:30 | Integrating proteomic networks with genetic coessentiality to analyze mammalian protein complexes Joshua Pan, Dana-Farber Cancer Institute, USA |
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11:30 - 11:45 |
An extracellular network of Arabidopsis leucine-rich repeat receptor kinases controls plant development and defenses |
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11:45 - 12:00 |
A synthetic-systems approach to the host-parasite interface: immunomodulation by parasitic nematodes |
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12:00 - 13:30 | Lunch in the ATC Foyer |
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13:30 - 17:00 |
Session 5: Network Mapping |
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13:30 - 14:00 |
Mapping the polarity interactome |
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14:00 - 14:30 | Enabling systems understanding through data integration & network-based visual analytics Jianguo (Jeff) Xia, McGill University, Canada |
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14:30 - 15:00 | Evolution and dynamics in protein networks from integration of interfaces and copy numbers Margaret Johnson, Johns Hopkins University, USA |
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15:00 - 15:30 |
Coffee Break & Meet the Invited Speakers: Mike Boxem, Jianguo Xia, Margaret Johnson, Luis Serrano |
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15:30 - 16:15 |
Keynote speaker: Luis Serrano |
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16:15 - 16:30 |
Points of crosstalk and signal transduction from a systematic experimental phytohormone |
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16:30 - 16:45 |
A protein interaction approach to human kinase phophorylation networks |
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16:45 - 17:00 |
Coordinating high-detail molecular interaction curation through the IntAct database |
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17:00 - 17:15 | Closing Remarks and Poster Prize |