Location & dates EMBL Heidelberg, Germany 10 - 13 Nov 2018
Deadlines Registration closed Abstract submission closed

EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.

Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.

More information for participants of events at EMBL Heidelberg can be found here.


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Day 1 - Saturday 10 November
13:00-15:00 Registration and Lunch
15:00-15:05 Welcome remarks

Session I
Chair: Eileen Furlong - EMBL Heidelberg, Germany


Nascent transcription profiling in single cells by intron seqFISH
Long Cai - California Institute of Technology, USA


Proteome dynamics
Matthias Selbach - Max Delbrück Center for Molecular Medicine, Germany


Determining protein structures using genetics
Joern Schmiedel - Centre for Genomic Regulation (CRG), Spain


High throughput yeast library generation for comparative cell analyses
Michael Knop - ZMBH, University of Heidelberg, Germany


Coffee Break


Integration of local and regional cis-regulatory information
Barak Cohen - Washington University in St. Louis, USA


Perturbing shape readout in vitro and in vivo provides mechanistic insight into adaptive DNA recognition by a multi-homeodomain complex
Judith Kribelbauer


Using single-cell transcriptomics and planarians to study stem cells, their differentiation and their evolution
Jordi Solana - Oxford Brookes University, UK


Reconstructing axolotl limb regeneration using single-cell transcriptomics
Barbara Treutlein - Max Planck Institute for Evolutionary Anthropology, Germany


Dinner in the Canteen

21:00-23:00 Drinks in ATC Roof Top Lounge 
Day 2 - Sunday 11 November

Session II 
Chair: Barbara Treutlein - Max Planck Institute for Evolutionary Anthropology, Germany

09:00-09:30 Thermal stability and solubility in molecular biology
Mikhail Savitski - EMBL Heidelberg, Germany

Using Machine Learning to Detect Enhancer Variation and Evolutionary Conservation
Michael Beer - Johns Hopkins University, USA

10:00-10:15 A rare codon-based translational program drives cell proliferation
Joao Guimaraes - University of Basel, Switzerland
10:15-10:45 Understanding cell-fate decisions to non-lethal dose of chemotherapy
Lani Wu - University of California San Francisco, USA
10:45-11:15 Coffee Break
11:15-11:45 The functional relevance of eukaryotic protein phosphorylation
Pedro Beltrao - EMBL-EBI Hinxton, UK

The Single Cell Landscape of Breast Cancer
Hartland Jackson - University of Zurich, Switzerland


Engineered chromatin readers reveal the proteome composition at key chromatin states in living cells
Baubec Tuncay - University of Zurich, Switzerland

12:15-12:45 DNA binding bispecificity by forkhead transcription factors
Martha Bulyk - Harvard Medical School, USA 



Poster Session I: Odd numbers


Session III - Chair: Joshua Coon - University of Wisconsin, USA


New technology for rapid and comprehensive proteome analysis
Joshua Coon - University of Wisconsin, USA


Cell-specific proteome analyses of human bone marrow reveal molecular features of age-dependent functional decline
Natalie Romanov - EMBL  Heidelberg, Germany


Mapping cellular memory at single cell resolution
Amos Tanay - Weizmann Institute, Israel


Coffee Break


Understanding enhancer usage during embryonic development at a single cell level
Eileen Furlong - EMBL Heidelberg, Germany


Decoding Chromatin Modification States Using Chemical Biology and Computational Proteomics
Till Bartke 


Big data and health
Mike Snyder - Stanford University, USA


Dinner in the Canteen

21:00-23:00 Drinks in ATC Roof Top Lounge
Day 3 - Monday 12 November
09:00-12:45 Session IV - Chair: Arnaud Krebs - EMBL Heidelberg, Germany
09:00-09:30 Probing protein structural changes on a proteome-wide scale
Paola Picotti - ETH Zurich, Switzerland
09:30-09:45 Meiotic Sex Chromosome Inactivation in the Drosophila melanogaster male germline
Brian Oliver - NIH, USA
09:45-10:00 Comprehensive characterization of protein abundance, stability and aggregation during vertebrate brain aging
Alessandro Ori - Leibniz Institute on Aging - Fritz Lipmann Institute, Germany
10:00-10:15 Single cell expression analysis uncouples transdifferentiation and reprogramming 
Mirko Francesconi - CRG, Spain
10:15-10:45 Lineage estimation from single-cell RNA-seq time-series
Fabian Theis - Helmholtz Zentrum München, Germany
10:45-11:15 Coffee Break

Transcription factor activity and nucleosome organisation in mitosis
Nick Owens, Institut Pasteur

11:30 - 11:45

Stress response dynamics that span different signaling pathways
Rati Sharma, Harvard University

11:45-12:00 Predicting complex genetic phenotypes using error propagation in weighted networks
Andrei Kucharavy - Johns Hopkins University, USA
12:00-12:15 Mutations in disordered regions can cause disease by creating dileucine motifs
Katrina Meyer - Max Delbrück Center for Molecular Medicine in the Helmholtz Association, German
12:15-12:45 Proximity-dependent biotinylation as a tool to understand
cellular signaling: revisiting Target of Rapamycin signaling
Anne-Claude Gingras - Lunenfeld-Tanenbaum Research Institute, Canada

Lunch, ATC Foyer


Poster Session II: Even numbers


Session V -  Chair: Paola Picotti, ETH Zurich, Switzerland


The tool of revelation: ionbot uncovers an exciting new view on the proteome
Lennart Martens - Ghent University, Belgium


Decoding SOX10 gene regulatory programs using time-series, single-cell, and cross-species chromatin profiling
Liesbeth Minnoye - VIB - KU Leuven, Belgium


Understanding principles of transcription regulation at the resolution of single DNA molecules
Arnaud Krebs - EMBL Heidelberg, Germany

17:45-18:15 Coffee Break
18:15-18:45 Genome-wide analysis of protein-DNA interactions
Jussi Taipale - Karolinska Institutet, Sweden
18:45-19:00 Identifying protein interactions relevant in cancer development 
Marija Buljan - ETH Zurich, Institute of Molecular Systems Biology, Switzerland

The Ups and Downs of Protein Expression Regulation in Response to Misfolding Stress
Christine Vogel - New York University, USA

19:30-24:00 Gala Dinner and party in the ATC
Day 4 - Tuesday 13 November

Session VI - Chair: Mikhail Savitski, EMBL Heidelberg, Germany


Functional characterization and therapeutic targeting of gene regulatory elements
Nadav Ahituv - University of California, San Francisco, USA


Mechanisms of neurogenic gene expression – Specific enhancer-regulator interactions with spatiotemporal resolution
Ana Luisa Guimarães - BIMSB-MDC, Germany


In vivo phosphoproteomics reveals pathogenic signaling changes in diabetic islets
Francesca Sacco - University of Rome Tor Vergata, Italy 


Divergent enhancers underlying rapid adaptation in natural stickleback populations
Stanley Neufeld - MPI for Developmental Biology, Germany


Identifying deleterious mutations across the proteome by limited mistranslation mutagenesis
Judith Villen - University of Washington, USA


Coffee Break


Proteomics for translational research
Matthias Mann - Max Planck Institute of Biochemistry, Germany


Leveraging transcription factor cooperativity for the discovery of protein-phenotype interactions
Ignacio Ibarra - EMBL Heidelberg, Germany


Clock-dependent chromatin topology modulates circadian transcription and behaviour
Jake Yeung - École Polytechnique Fédérale de Lausanne, Switzerland

12:15-12:45 Multiplexed protein maps link subcellular organization to cellular states
Lucas Pelkmans - University of Zurich, Switzerland
12:45-13:00 Closing Remarks
13:00 Packed lunch
13:15 Buses downtown and Frankfurt Airport