Coronavirus information for participants
The onsite course and conference programme at EMBL has been paused until the end of June 2020.
We aim to continue offering our advanced training for the scientific community however we safely can. While some events have been cancelled, many have been rescheduled for a later date and others will be delivered as virtual events.
Registration is open for onsite courses and conferences starting after 1 July and for the virtual events. All registration fees for any events which don’t take place due to the COVID-19 disruption are fully refundable.
More information for participants of events at EMBL Heidelberg can be found here.
Programme
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| Time | Speaker | |
|---|---|---|
| 11:00-13:00 | Arrival / Registration with light refreshments Pre-conference workshop hosted by Samplix at 11:30-12:30 in Helix Seminar Room A |
|
| 13:00-13:15 | Opening remarks | |
| 13:15-16:30 |
Session 1: Cancer genetics and mutation |
|
| 13:15-13:45 |
Somatic evolution in healthy and diseased bladder urothelium |
|
| 13:45-14:00 |
A Pan-Cancer Analysis reveals Nonstop Mutations causing SMAD4 Tumor Suppressor Degradation |
|
| 14:00-14:15 |
Large-scale analysis of liver cancer evolution in five species |
|
| 14:15-14:45 |
Full-length transcript isoforms associated with SF3B1 mutation in chronic lymphocytic leukemia |
|
| 14:45-15:15 |
Coffee break |
|
| 15:15-15:45 |
Understanding epitopes that drive T cell activation in cancer |
|
| 15:45-16:00 |
Comparison of somatic mutational processes across mammalian species |
|
| 16:00-16:15 |
Genotoxic pks+ E. coli induces a unique mutational signature in human colorectal cancer |
|
| 16:15-16:30 |
Oxidative DNA damage repair switches mutagenic outcomes in coding sequence dependent on the epigenome |
|
| 16:30-17:00 |
Coffee break |
|
| 17:00-18:00 |
Keynote: |
|
| 18:00-18:45 |
Digital poster presentations (Poster numbers 38, 45, 101, 107, 123, 124, 136, 137, 144, 146, 155, 157, 158) and Meet the speakers of Day 1 in the ATC Foyer |
|
| 18:45-20:15 | Dinner in the EMBL Canteen | |
| 20:15-22:00 | After-dinner drinks in the ATC Rooftop Lounge |
|
| Time | Speaker | |
|---|---|---|
| 09:00-12:15 | Session 2: Cancer & microenvironment: immunogenomics & single cells Chairs: Elli Papaemmanuil & Peter Campbell |
|
| 09:00-09:30 |
Building personalized cancer vaccines |
|
| 09:30-09:45 |
Single-cell transcriptomics predicts relapse in infants with acute lymphoblastic leukemia |
|
| 09:45-10:00 |
Computational study of the mechanisms of response to immunotherapy by transcriptomic analysis of the tumor immune microenvironment in melanoma |
|
| 10:00-10:30 |
Tumor Genomic Profiling to Identify Therapeutic Biomarkers and Guide Clinical Care |
|
| 10:30-11:00 |
Coffee break |
|
| 11:00-11:30 |
Somatic mutations in normal tissues |
|
| 11:30-11:45 | Complex genomic rearrangements induced by ionizing radiation in normal cells Jeonghwan Youk, Korea Advanced Institutue of Science and Technology (KAIST), Republic of Korea |
|
| 11:45-12:00 |
Lack of HLA affinity-based neoantigen depletion signals in the cancer genome when considering mutational sequence contexts |
|
| 12:00-12:15 |
Life History of Normal Human Lymphocytes Revealed By Somatic Mutations |
|
| 12:15-13:45 |
Lunch |
|
| 13:45-15:15 |
Poster Session 1 (odd numbers) |
|
| 15:15-18:00 |
Session 3: Cancer genome and epigenome |
|
| 15:15-15:45 |
Deciphering the evolutionary paths of tumor progression in Small Cell Lung Cancer |
|
| 15:45-16:00 |
Epigenetic and transcriptional reprogramming underlies lung adenocarcinoma histological intra-tumor heterogeneity and microenvironment composition |
|
| 16:00-16:15 |
Reconstructing shattered chromosomes in oesophageal adenocarcinomas |
|
| 16:15-16:45 |
Genomic Alterations Across Molecular Subtypes of Mantle Cell Lymphoma |
|
| 16:45-17:15 | Coffee break & Meet the speakers of Day 2 |
|
| 17:15-17:30 | Aberrant integration of Hepatitis B virus DNA promotes restructuring of hepatocellular carcinoma genome Eva Alvarez, CIMUS, University of Santiago de Compostela, Spain |
|
| 17:30-18:00 |
Decoding pancreatic cancer through large scale cohort and single cell sequencing |
|
| 18:00-19:00 | Keynote: Partnering with patients to accelerate cancer genomics and precision medicine Nikhil Wagle, Dana-Farber Cancer Institute, USA |
|
| 19:00-19:15 | Apéritif in the ATC Foyer | |
| 19:15-21:15 |
Conference Dinner in the EMBL Canteen |
|
| 21:15-00:00 | Conference Party with DJ in the ATC Foyer |
|
| Time | Speaker | |
|---|---|---|
| 09:00-12:00 | Session 4: Drivers of cancer and genome-wide functional screens Chairs: Angela Brooks & Peter J.M. Valk |
|
| 09:00-09:30 | Accelerating prediction of tumor vulnerabilities using precision functional genomics Jesse S. Boehm, Broad Institute, USA |
|
| 09:30-09:45 |
The U1 Spliceosomal RNA is Recurrently Mutated in Multiple Cancers |
|
| 09:45-10:00 |
Functional genomic studies of cancer immune evasion using in vitro and in vivo CRISPR/Cas9 genetic screens |
|
| 10:00-10:30 |
The mutational footprints of cancer therapies |
|
| 10:30-11:00 | Coffee break | |
| 11:00-11:30 |
Jan Korbel, EMBL Heidelberg, Germany |
|
| 11:30-11:45 |
Uncovering the role of the disruption of ubiquitin mediated proteolysis in tumorigenesis |
|
| 11:45-12:00 |
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers |
|
| 12:00-13:30 | Lunch |
|
| 13:30-15:00 | Poster Session 2 (even numbers) | |
| 15:00-17:00 |
Session 5: Cancer genome medicine |
|
| 15:00-15:30 |
Mathew Garnett, Wellcome Trust Sanger Institute, UK |
|
| 15:30-15:45 | The Evolutionary Dynamics and Fitness Landscape of Clonal Haematopoiesis Jamie Blundell, University of Cambridge, UK |
|
| 15:45-16:00 | CRUK Grand Challenge Mutographs: Mutation signature analysis of Oesophageal Squamous Cell Carcinoma (ESCC) from high incidence regions Sarah Moody, Wellcome Sanger Institute, UK |
|
| 16:00-16:30 |
Oncologic therapy shapes the fitness landscape of clonal hematopoiesis |
|
| 16:30-17:00 |
NGS-based molecular minimal residual disease detection in acute myeloid leukemia |
|
| 17:00-17:15 | Closing remarks and poster prize | |
| 17:30 |
Bus departures downtown |
|