Location & dates EMBL Heidelberg, Germany 3 - 8 Nov 2019
Deadlines Application closed
organiser_EMBO_Course_2017

EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.


Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Programme

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Day 1 - Sunday 3 November 2019
TimeSpeakerLocation
10:40

Bus departure to EMBL Heidelberg

Holiday Inn ExpressHeidelberg - City Centre
11:00 - 12:00

Arrival and registrations with light lunch

12:00 - 12:15

Welcome & introduction
Yvonne Yeboah - EMBL Heidelberg, Germany

Flex Lab A & B

12:15 - 13:00

Lecture: Humanized mice: from academia to a global market
Leonard Shultz - The Jackson Laboratory, USA

Flex Lab A & B

13:00 - 15:00

5 min flash talks by speakers
Chair: Renata Stripecke - Hannover Medical School, Germany

Flex Lab A & B

15:00 - 17:00

5 min flash talks by participants
Chair: Brian Soper - The Jackson Laboratory, USA

Flex Lab A & B

17:00

Bus departure to Neckarmünzplatz

EMBL bus stop

17:30 - 20:00

Guided tour of Heidelberg and casual dinner (reservation for 19:30)

Urban Kitchen

Day 2 - Monday 4 November 2019
TimeSpeakerLocation
08:25

Bus departure to EMBL Heidelberg

Holiday Inn ExpressHeidelberg - City Centre

Part 1: Reconstructing the human immune system in vivo
Chair: Renata Stripecke - Hannover Medical School, Germany

09:00 - 09:45

Lecture: HSCs and human hematopoiesis in vivo
Dominique Bonnet - The Francis Crick Institute, UK

Flex Lab A & B

09:45 - 10:30

Lecture: New strains, immunity and autoimmunity
Michael Brehm - University of Massachusetts Medical School, USA

Flex Lab A & B

10:30 - 11:00

Coffee break

Flex Lab A & B

11:00 - 11:45

Lecture: T and NK cell development
James Di Santo - Institut Pasteur, France

Flex Lab A & B

11:45 - 12:30

Lecture: Human adaptive T and B immunity
Renata Stripecke - Hannover Medical School, Germany

Flex Lab A & B

12:30 - 13:30

Lunch break

EMBL Canteen

13:30 - 14:00

Lecture: Tools and optimized workflows for the analysis of human cells from humanized mouse models
David Agorklu - Miltenyi Biotech, Germany

Flex Lab A & B

14:00 - 14:30

Lecture: Multicolor flow cytometry
Diana Ordonez - EMBL Heidelberg, Germany

Flex Lab A & B
14:30 - 18:00

Practical: Selection of human hematopoietic stem cells, T cells, monocytes for humanization, harvest tissues from humanized mice and analyses of immune reconstitutions by FACS
Corinna Klein - Heidelberg Institute for Steam Cell technology and Experimental Medicine, Germany
Diana Ordonez - EMBL Heidelberg, Germany
Sebastian Theobald - Hannover Medical School, Germany

Training Lab B
18:00 - 19:00

Dinner

EMBL Canteen

19:00 - 21:00

Poster Session (Odd Numbers)

top of Helix B

21:00

Bus departure to Holiday Inn ExpressHeidelberg - City Centre

EMBL bus stop

Day 3 - Tuesday 5 November 2019
TimeSpeakerLocation
08:25

Bus departure to EMBL Heidelberg

Holiday Inn ExpressHeidelberg - City Centre

Part 2: Infections with human pathogens
Chair: Christian Muenz - University of Zurich, Switzerland

09:00 - 09:45

Lecture: EBV and KSV infections
Christian Muenz - University of Zurich, Switzerland

Flex Lab A & B

09:45 - 10:30

Lecture: Adenovirus and Ebola virus infections
Estefania Rodriguez-Burgos - Heinrich Pette Institute Hamburg, Germany

Flex Lab A & B

10:30 - 11:00

Coffee break

Flex Lab A & B

11:00 - 11:45

Lecture: B cell responses against HIV
Florian Klein - Centre for Molecular Medicine Cologne, Germany

Flex Lab A & B

11:45 - 12:30

Lecture: Gene therapy against HIV
Scott Kitchen - University of California Los Angeles, USA

Flex Lab A & B

12:30 - 13:30

Lunch break

EMBL Canteen

13:30 - 14:00

Lecture: Histopathology
Estefania Rodriguez-Burgos - Heinrich Pette Institute Hamburg, Germany

Flex Lab A & B

14:00 - 14:30

Lecture: Quantitative PCR
Kanika Vanshylla - Center for Molecular Medicine Cologne, Germany

Flex Lab A & B

14:30 - 18:00

Practical: RNA samples obtained from mice with infections ( HIV, AdV, EBV,HCMV, Ebola) analyzed by real time quantitative PCR for quantification of infections. Pre-fixated tissue sections and cells analyzed for detection of viral antigens by microscopy
Scott Kitchen - University of California Los Angeles, USA
Kanika Vanshylla - Center for Molecular Medicine Cologne, Germany
Estefania Rodriguez-Burgos - Heinrich Pette Institute Hamburg, Germany

Training Lab B
18:00 - 21:00

Pizza and Poster Session (Even Numbers)

top of Helix B

21:00

Bus departure to Holiday Inn ExpressHeidelberg - City Centre

EMBL bus stop

Day 4 - Wednesday 6 November 2019
TimeSpeakerLocation
08:25

Bus departure to EMBL Heidelberg

Holiday Inn ExpressHeidelberg - City Centre

Part 3: Patient derived transplants (PDX) for oncology research
Chair: J.J. Schuringa - University of Groningen, The Netherlands

09:00 - 09:45

Lecture: Ossicle implants for engraftment of hematopoietic stem cells and leukemia
J.J. Schuringa - University of Groningen, The Netherlands

Flex Lab A & B

09:45 - 10:30

Lecture: PDX models combined with human immune system
Brian Soper - The Jackson Laboratory, USA

Flex Lab A & B

10:30 - 11:00

Coffee break

Flex Lab A & B

11:00 - 11:45

Lecture: Minimal Information for Patient-Derived Tumor Xenograft Models
Terrence Meehan - EMBL-EBI Hinxton, UK

Flex Lab A & B

11:45 - 12:30

Lecture: Population-scale studies with PDX for precision medicine for colorectal cancer research
Livio Trusolino - University of Torino Medical School, Italy

Flex Lab A & B

12:30 - 13:30

Lunch break

EMBL Canteen

13:30 - 14:30

Lecture: In silico genomics analyses
Terrence Meehan - EMBL-EBI Hinxton, UK
J.J. Schuringa - University of Groningen, The Netherlands
Livio Trusolino - University of Torino Medical School, Italy

Flex Lab A & B

14:30 - 18:00

Practical: In silico genomics analyses of mutations and tumor heterogeneity analyses, representative examples
Terrence Meehan - EMBL-EBI Hinxton, UK
Ross Thorne - EMBL-EBI Hinxton, UK
J.J. Schuringa - University of Groningen, The Netherlands
Livio Trusolino - University of Torino Medical School, Italy

Computer Training Lab
18:00 - 19:00

Dinner

EMBL Canteen

19:00 - 21:00

Selected short talks (4x) and round table discussion: challenges in the field

Flex Lab A & B

21:00

Bus departure to Holiday Inn ExpressHeidelberg - City Centre

EMBL bus stop

Day 5 - Thursday 7 November 2019
TimeSpeakerLocation
08:25

Bus departure to EMBL Heidelberg

Holiday Inn ExpressHeidelberg - City Centre

Part 4: Immuno-oncology and transplantation
Chair: Brian Soper - The Jackson Laboratory, USA

09:00 - 09:45

Lecture: Genetic heterogeneity of AML and pancreatic cancer
Andreas Trumpp - German Cancer Research Center , Germany

Flex Lab A & B

09:45 - 10:30

Lecture: Immuno-oncology of breast cancer
Anja Wege - University Medical Center Regensburg, Germany

Flex Lab A & B

10:30 - 11:00

Coffee break and Group Photo

Flex Lab A & B

11:00 - 11:45

Lecture: Application of PDX for triple negative marker breast cancer research
Carol Bult - The Jackson Laboratory, USA

Flex Lab A & B

11:45 - 12:30

Lecture: Humanized mice and organoids in transplantation research
Kourosh Saeb-Parsy - University of Cambridge, UK

Flex Lab A & B

12:30 - 13:30

Lunch break

EMBL Canteen

13:30 14:30

Lecture: Video
Brian Soper - The Jackson Laboratory, USA
Li-Chin Yao - The Jackson Laboratory, USA

Flex Lab A & B

14:30 - 18:00

Practical: Humanized mice implanted with patient-derived malignancies
Anja Wege - University Medical Center Regensburg, Germany
Li-Chin Yao - The Jackson Laboratory, USA
Kourosh Saeb-Parsy - University of Cambridge, UK

Training Lab B
18:00

Bus departure to Holiday Inn ExpressHeidelberg - City Centre

19:00

Bus departure to Wirtshaus zum Nepomuk (walk from the Old Bridge)

Old Bridge
19:30

Dinner Downtown

Wirtshaus zum Nepomuk

Day 6 - Friday 8 November 2019
TimeSpeakerLocation
08:25

Bus departure to EMBL Heidelberg

Holiday Inn ExpressHeidelberg - City Centre

Part 5: Regenerative medicine and the regulatory perspective
Karl-Dimiter Bissig - Duke University Medical Center, USA

09:00 - 09:30

Lecture: Human liver chimeric mouse models – the chances & challenges
Karl-Dimiter Bissig - Duke University Medical Center, USA

Flex Lab A & B

09:30 - 10:00

Lecture: Overcoming liver injury through regenerative medicine
Amar Sharma - Hannover Medical School, Germany

Flex Lab A & B

10:00 - 10:30

Lecture: Tissue immunophenotyping and cell quantifications
Silvia Guionaud - AstraZeneca, UK

Flex Lab A & B

10:30 - 11:00

Coffee break

Flex Lab A & B

11:00 - 11:45

Lecture: Humanized mice in drug discovery
Johannes Sam - Roche Zurich, Switzerland

Flex Lab A & B

11:45 - 12:30

Lecture: The regulatory perspective of the FDA
Kristina Howard - Food and Drug Administration, USA

Flex Lab A & B

12:30 - 13:30

Lunch break

EMBL Canteen

13:30 - 14:30

Round table discussion and closing remarks

Flex Lab A & B

14:30

Bus departure to Hauptbahnhof, Crowne Plaza, Holiday Inn Express Heidelberg City Centre

EMBL bus stop