Session 1: Molecular Basis of Health and Disease
Chair: TBC

Understand the similarities and differences between normal and malignant stem cells to develop more efficient therapies for AML patients
Caroline Pabst - Heidelberg University Hospital, Germany

Understanding genetic and epigenetic T-cell regulatory mechanisms in autoimmune diseases
Neha Daga - EMBL Heidelberg, Germany

Functional fine-mapping of immune disease variants points towards gene expression modulation in CD4 regulatory T cells
Gosia Trynka - Wellcome Sanger Institute, UK 

Coffee Break and Meet the Speakers in ATC Foyer

Spatial proteomics and cell biology
Emma Lundberg - KTH Royal Institute of Technology, Sweden 

Whole genome sequencing insights into infertility: Preliminary results from WGS of couples with repeated IVF failure
Anna Mantzouratou - Bournemouth University, UK

Bioinformatics for personalized medicine: Looking beyond the genome
Christoph Bock - CeMM Research Center for Molecular Medicine, Austria

Keynote Lecture: Precision health: Stem cell based technologies
Hiromitsu Nakauchi - Stanford University, USA 

Speed Networking Session in ATC Foyer

Dinner in EMBL Canteen

Welcome Reception in ATC Rooftop Lounge

Pinpointing disease-causing regulatory genetic variants by multi-omics and machine learning
Julien Gagneur - Technical University of Munich, Germany 

Characterizing the phenotypic effects of genetic variants associated with transcriptomic outliers in iPSC and differentiated cell-types
Craig Smail - Stanford University, USA

Data integration for prediction of time to insulin in type 2 diabetes patients
Rikke Linnemann Nielsen - Technical University of Denmark, Denmark

The power of multi-omics for finding novel disease stratifications
Wolfgang Huber - EMBL Heidelberg, Germany 

Coffee Break and Meet the Speakers in ATC Foyer

Population genomics and genetics of complex traits
Emmanouil Dermitzakis - University of Geneva Medical School, Switzerland

A longitudinal big data approach for precision health
Sophia Miryam Schüssler-Fiorenza Rose - Stanford University, USA

Multiplexed Cas12a-Cpf1-based screening enables machine learning prediction of an optimal evolving barcoding strategy for targeted therapy drug resistance characterization in cancer
Nicholas Hughes - Stanford University, USA

Computation approaches to understanding the genotype-phenotype map on a genome-wide scale
Oliver Stegle - EMBL Heidelberg and German Cancer Research Center, Germany

Lunch and Meet the Editors in ATC Foyer

Session 3: Clinical, Ethical and Societal Issues
Chair: TBC

Novel application of sequencing technologies to non-invasive diagnostics, immune repertoire analysis, and de novo genome sequencing
Stephen Quake - Stanford University, USA 

Microbiome in active and in active older people
Nathan O'Callaghan - CSIRO, Australia

The value(s) of Precision Health: Patients and society
Barbara Prainsack - King's College London, UK and University of Vienna, Austria 

Coffee Break and Meet the Speakers in ATC Foyer

Big data in health and biology 
Ewan Birney - EMBL-EBI Hinxton, UK

Keynote Lecture: Genetic and epigenetic variation and their impact on chromosome conformation and gene expression differences in development and disease. Using X inactivation and autosomal monoallelic gene expression as model systems
Edith Heard - EMBL Heidelberg, Germany

Flash Talks Session

Poster Session 1 (odd numbers)
with beer, wine and snacks

Longitudinal sampling of menstrual fluid for applications in early detection and monitoring of gynaecological malignancy
Angela Goncalves - German Cancer Research Center, Germany

Identification of a reproducible epigenetic risk profile for schizophrenia linked to post-mortem brain methylation and prefrontal-hippocampal connectivity
Emanuel Schwarz - Central Institute of Mental Health, Germany

The use of iPSCs for in vivo personalized organ generation using cross-species chimeras: A primate model
Morteza Roodgar - Stanford University, USA

Harnessing big data for personalized medicine
Eran Segal - Weizmann Institute of Science, Israel 

Coffee Break and Meet the Speakers in ATC Foyer

Personalizing ICU meditine: How genomics is advancing our understanding of ARDS
Angela Rogers - Stanford University, USA

Selected short talk

Navigating causal-reasoning pathways to identify personalize drug-treatments through multi-omics using multi-task learning
Rosa Hernansaiz Ballesteros - Heidelberg University, Germany

Ex vivo drug efficacy testing on patient-derived cells combined with omics profiling to personalize treatment
Olli Kallioniemi - Karolinska Institutet, Sweden 

Lunch in ATC Foyer

Unlocking the secret genes and genomes from the human microbiome
Ami Bhatt - Stanford University, USA 

DNA methylation relates to cardiac alternative splicing in dilated cardiomyopathy
Weng-Tein Gi - Heidelberg University, Germany

Quantitative measurement of full-length transcript isoforms reveals precise regulation of splicing in human heart cells
Chenchen Zhu - Stanford University, USA

Patient centered data in real world medicine
Christof von Kalle - Charité - Berlin Institute of Health, Germany and Sidra Medicine, Qatar

Poster Session 2 (even numbers)
with beer, wine and snacks

Conference Dinner in EMBL Canteen

Conference Party with Live Band in ATC Foyer

Theranostic designer cell implant design to correct prominent metabolic disorders
Martin Fussenegger - ETH Zurich, Switzerland 

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
Tejaswini Mishra - Stanford University, USA

Development of a urine-based diagnostic test for selecting a subpopulation of asthmatics
Hoda Sharifian - AstraZeneca, Sweden

Development of microfluidic technology to address complex questions in biomedical sciences and developmental biology
Christoph Merten - EMBL Heidelberg, Germany

Ultrasensitive Protein Measurements for Early Disease Detection
David Walt - Wyss Institute at Harvard University, USA 

Lunch in EMBL Canteen

Session 6: Disease Models
Chair: TBC

The failure uncovers heart's wonderful principles
Benjamin Meder - Heidelberg University Hospital, Germany 

Pathological mutations in LSD1 interfere with ZEB1/2 transcription factor and alter developmental gene expression
Daria Bunina - EMBL Heidelberg, Germany

Extending the small molecule similarity principle to all levels of biology
Patrick Aloy - Institute for Research in Biomedicine, Spain 

Extracellular electrophysiological characterization of neurons and networks at subcellular resolution
Andreas Hierlemann - ETH Zurich, Switzerland