Location & dates EMBL Heidelberg, Germany 13 - 16 Nov 2019
Deadlines Registration closed Abstract submission closed
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Programme

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Day 1 - Wednesday 13 November 2019
TimeSpeaker
12:00 - 13:30 Arrival and Registration
with light lunch
13:30 - 13:45 Opening Remarks
13:45 - 18:00

Session 1
Chair: Lars Steinmetz

13:45 - 14:15

Understand the similarities and differences between normal and malignant stem cells to develop more efficient therapies for AML patients
Caroline Pabst - University Hospital Heidelberg, Germany

14:15 - 14:45 Regulatory principles governing enhancer activity in development and disease
Emma Farley - University of California, San Diego, USA 
14:45 - 15:00

Understanding genetic and epigenetic T cell regulatory mechanisms in autoimmune diseases
Neha Daga - EMBL Heidelberg, Germany

15:00 - 15:30

Translating immune disease GWAS variants to causal cell types and genes
Gosia Trynka - Wellcome Sanger Institute, UK 

15:30 - 16:00

Coffee Break and Meet the Speakers in ATC Foyer with:
Caroline Pabst - University Hospital Heidelberg, Germany
Emma Farley - University of California, San Diego, USA
Gosia Trynka - Wellcome Sanger Institute, UK
Emma Lundberg - Science for Life Laboratory, KTH Royal Institute of Technology, Sweden
Christoph Bock - CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria
Hiromitsu Nakauchi - Stanford University School of Medicine, USA 

16:00 - 16:30

Dissecting spatiotemporal variations of the human proteome
Emma Lundberg - Science for Life Laboratory, KTH Royal Institute of Technology, Sweden 

16:30 - 16:45

Whole genome sequencing insights into infertility: Preliminary results from WGS of couples with repeated IVF failure
Anna Mantzouratou - Bournemouth University, UK

16:45 - 17:15

Single cell sequencing of epigenetic disease landscapes and induced perturbations
Christoph Bock - CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Austria

17:15 - 18:00

Keynote Lecture: Growing organs in vivo: iPS cell derived, xeno created organs for transplantation
Hiromitsu Nakauchi - Stanford University School of Medicine, USA 

18:00 - 19:30

Speed Networking Session in ATC Foyer

19:30 - 21:00

Dinner in EMBL Canteen

21:00 - 23:00

Welcome Reception in ATC Rooftop Lounge

Day 2 - Thursday 14 November 2019
TimeSpeaker
09:00 - 12:30 Session 2
Chair: Julien Gagneur
09:00 - 09:30

Pinpointing disease causing regulatory genetic variants by multi omics and machine learning
Julien Gagneur - Technical University of Munich, Germany 

09:30 - 09:45

Characterizing the phenotypic effects of genetic variants associated with transcriptomic outliers in iPSC and differentiated cell types
Craig Smail - Stanford University, USA

09:45 - 10:00

Data integration for prediction of time to insulin in type 2 diabetes patients
Rikke Linnemann Nielsen - Technical University of Denmark, Denmark

10:00 - 10:30

The power of multi omics for finding novel disease stratifications
Wolfgang Huber - EMBL Heidelberg, Germany 

10:30 - 11:00

Coffee Break and Meet the Speakers in ATC Foyer with:
Julien Gagneur - Technical University of Munich, Germany
Wolfgang Huber - EMBL Heidelberg, Germany
Emmanouil Dermitzakis - University of Geneva Medical School, Switzerland
Barbara Prainsack - University of Vienna, Austria 

11:00 - 11:30

Genetic variation in 3D cis and trans genome interactions in immune cells
Emmanouil Dermitzakis - University of Geneva Medical School, Switzerland

11:30 - 11:45

A longitudinal big data approach for precision health
Sophia Miryam Schüssler-Fiorenza Rose - Stanford University, USA

11:45 - 12:00

Multiplexed Cas12a Cpf1 based screening enables machine learning prediction of an optimal evolving barcoding strategy for lineage tracing
Nicholas Hughes - Stanford University, USA

12:00 - 12:30

The value(s) of precision health: Patients and society
Barbara Prainsack - University of Vienna, Austria 

12:30 - 14:00

Lunch and Meet the Editors in ATC Foyer with:
Celine Carret - EMBO, Germany
Joao Duarte - Springer Nature, Germany
Maria Polychronidou - Molecular Systems Biology, Germany

14:00 - 18:00

Session 3
Chair: Ami Bhatt

14:00 - 14:30

Precision medicine from liquid biopsies
Stephen Quake - Stanford University, USA 

14:30 - 14:45

Microbiome in active and inactive older people
Nathan O'Callaghan - CSIRO, Australia

14:45 - 15:15 Functional precision medicine for tailoring treatments to patients with acute myeloid leukemia
Olli Kallioniemi - Science for Life Laboratory, Karolinska Institutet, Sweden 
15:15 - 15:45

21st Century medicine: Big data, wellness and disease
Leroy Hood - Institute for Systems Biology, USA

15:45 - 16:15

Coffee Break and Meet the Speakers in ATC Foyer with:
Stephen Quake - Stanford University, USA
Olli Kallioniemi - Karolinska Institutet, Sweden
Leroy Hood - Institute for Systems Biology, USA
Ewan Birney - EMBL-EBI Hinxton, UK
Edith Heard - EMBL Heidelberg, Germany

16:15 - 16:45

Big data in health and biology 
Ewan Birney - EMBL-EBI Hinxton, UK

16:45 - 17:30

Keynote Lecture: Exploring the dynamic relationship between gene expression and chromosome organisation during X chromosome inactivation
Edith Heard - EMBL Heidelberg, Germany

17:30 - 18:00

Flash Talks Session
#47 Katharina Beuke - Sanofi, Germany
#48 Etienne Boileau - Klaus Tschira Institute for Integrative Computational Cardiology, Germany
#51 Giacomo Corleone - Istituti Fisioterapici Ospitalieri, Italy
#53 Annisa Fitriani - Ananda Purworejo Hospital, Indonesia
#60 Bence Keömley-Horváth - Pázmány Péter Catholic University, Hungary
#64 Roman Kurilov - German Cancer Research Center, Germany
#68 Chen Li - ETH Zürich, Switzerland
#70 Vladislav Lysenkov - Turku Bioscience, Finland
#72 Enrico Mossotto - University of Southampton, United Kingdom
#76 Wendelin Schramm - GECKO Institute, Heilbronn University, Germany
#81 George Spyrou - The Cyprus Institute of Neurology and Genetics, Cyprus
#82 Ben Story - EMBL Heidelberg, Germany

18:00 - 19:30

Poster Session 1 (odd numbers)
with beer, wine and snacks

19:30 - 21:00 Dinner in EMBL Canteen
Day 3 - Friday 15 November 2019
TimeSpeaker
09:00 - 12:30 Session 4
Chair: Emma Lundberg
09:00 - 09:30

Microfluidic approaches in personalized cancer therapy
Christoph Merten - EMBL Heidelberg, Germany

09:30 - 09:45

Identification of a reproducible epigenetic risk profile for schizophrenia linked to post mortem brain methylation and prefrontal hippocampal connectivity
Emanuel Schwarz - Central Institute of Mental Health, Germany

09:45 - 10:00

The use of iPSCs for in vivo personalized organ generation using cross species chimeras: A primate model
Morteza Roodgar - Stanford University, USA

10:00 - 10:30

Harnessing big data for personalized medicine
Eran Segal - Weizmann Institute of Science, Israel 

10:30 - 11:00

Coffee Break and Meet the Speakers in ATC Foyer with:
Christoph Merten - EMBL Heidelberg, Germany
Eran Segal - Weizmann Institute of Science, Israel
Angela Rogers - Stanford University, USA
Oliver Stegle - EMBL Heidelberg and German Cancer Research Center, Germany

11:00 - 11:30

Personalizing ICU medicine: How 'omics is advancing our understanding of ARDS
Angela Rogers - Stanford University, USA

11:30 - 11:45

Integrated personalized diabetes management goes Europe: Adding value to diabetes care through digital innovation and integrated care
Allan Jones - Roche Diabetes Care Deutschland, Germany

11:45 - 12:00

Navigating causal reasoning pathways to identify personalize drug treatments through multi omics using multi task learning
Rosa Hernansaiz Ballesteros - Heidelberg University, Germany

12:00 - 12:30

Unravelling the genotype-to-phenotype map in human pluripotent cells
Oliver Stegle - EMBL Heidelberg and German Cancer Research Center, Germany

12:30 - 14:00

Lunch in ATC Foyer

14:00 - 18:00

Session 5
Chair: Angela Rogers

14:00 - 14:30

Unlocking the secret genes and genomes from the human microbiome
Ami Bhatt - Stanford University, USA 

14:30 - 14:45

DNA methylation relates to cardiac alternative splicing in dilated cardiomyopathy
Weng-Tein Gi - Heidelberg University, Germany

14:45 - 15:00

Single molecule, full length transcript sequencing reveals disease associated isoforms in human cells
Chenchen Zhu - Stanford University, USA

15:00 - 15:15

Pathological mutations in LSD1 interfere with ZEB1/2 transcription factor and alter developmental gene expression
Daria Bunina - EMBL Heidelberg, Germany

15:15 - 15:45

Patient centered data in real world medicine
Christof von Kalle - Berlin Institute of Health - Charité Clinical Study Center, Germany

15:45 - 16:15

Coffee Break and Meet the Speakers in ATC Foyer with:
Ami Bhatt - Stanford University, USA
Christof von Kalle - Berlin Institute of Health - Charité Clinical Study Center, Germany
Ruedi Aebersold - ETH Zürich, Switzerland
Christina Curtis - Stanford University, USA

16:15 - 16:45 The modular proteome and its clinical significance
Ruedi Aebersold - ETH Zürich, Switzerland 
16:45 - 17:15 From bench to bedside: Identifying and targeting the genomic drivers of breast cancer progression and therapeutic resistance
Christina Curtis - Stanford University, USA
17:15 - 18:00 Industry Panel Discussion: Commercialising Precision Health
Moderator: Michael Snyder
Panel members:
Gitte Neubauer - Cellzome, Germany
Eran Segal - Weizmann Institute of Science, Israel 
Christian Fegeler - MOLIT Institute, Germany
18:00 - 19:30

Poster Session 2 (even numbers)
with beer, wine and snacks

19:30 - 21:00

Conference Dinner in EMBL Canteen

21:00 - 00:00

Conference Party with Live Band "The Taylor Brothers" in ATC Foyer

Day 4 - Saturday 16 November 2019
TimeSpeaker
09:00 - 12:15

Session 6
Chair: Judith Zaugg

09:00 - 09:30

Making meaningful biomarker measurements with digital ELISA technology
David Walt - Wyss Institute at Harvard University, Harvard Medical School, Brigham and Women's Hospital, USA 

09:30 - 09:45

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight
Tejaswini Mishra - Stanford University, USA

09:45 - 10:15

Designing cell-based treatment strategies of the future
Martin Fussenegger - ETH Zurich, Switzerland

10:15 - 10:45

Extracellular electrophysiological characterization of neurons and networks at subcellular resolution
Andreas Hierlemann - ETH Zürich, Switzerland

10:45 - 11:15

Coffee Break and Meet the Speakers in ATC Foyer with:
David Walt - Wyss Institute at Harvard University, Harvard Medical School, Brigham and Women's Hospital, USA
Martin Fussenegger - ETH Zurich, Switzerland 
Andreas Hierlemann - ETH Zürich, Switzerland
Patrick Aloy - Institute for Research in Biomedicine, Spain
Benjamin Meder - University Hospital Heidelberg, Germany

11:15 - 11:45

Extending the small molecule similarity principle to all levels of biology
Patrick Aloy - Institute for Research in Biomedicine, Spain 

11:45 - 12:15

The failure uncovers heart’s wonderful principles
Benjamin Meder - University Hospital Heidelberg, Germany 

12:15 - 12:30 Closing Remarks and Poster Prizes
12:30 Packed Lunch and Departure