Location & dates EMBL Heidelberg, Germany 7 - 9 Mar 2019
Deadlines Registration closed Abstract submission closed
organiser_WGC

Programme

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Day 1 - Thursday 7 March 2019
TimeSpeaker
11:00 - 12:30 Registration and light refreshments
12:30 - 12:45 Opening remarks
12:45 - 13:30
Keynote Speaker
Ubiquitin Mediated Regulation of Transcription Factor Stability
Vishva Dixit - Genentech, USA
13:30 - 16:30 Session 1: Cell Biology
Chair: Michal Sharon - Weizmann Institute, Israel
13:30 - 14:00

MAPPing the degradation landscape via proteasomal profiling
Yifat Merbl Weizmann Institute, Israel

14:00 - 14:30

Dissecting oncogenic EGF receptor signaling in-vivo by quantitative interaction proteomics and phosphoproteomics
Jesper Olsen  - University of Copenhagen, Denmark

14:30 - 15:00

Coffee break and Meet the Speakers: Vishva Dixit, Yifat Merbl

15:00 - 15:30

Exploring proteome and organelle homeostasis mechanisms using quantitative proteomics
Wade Harper - Harvard Medical School, USA

15:30 - 15:45

Decoding Chromatin Modification States Using Chemical Biology and Computational Proteomics
Till Bartke - Helmholtz Zentrum München, Germany

15:45 - 16:00

Quantitative analysis of murine T lymphocyte proteomes
Alejandro Brenes - University of Dundee, United Kingdom

16:00 - 16:15

Decoding Proteostasis: Understanding how proteome foldedness changes under proteostasis stress
Dezerae Cox - Bio21 Institute, University of Melbourne, Australia

16:15 - 16:30

The Solute Carrier Transporters Interactome
Alvaro Ingles Prieto - CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. Vienna, Austria

16:30 - 17:15

Flash talks (odd numbers 1 slide / 1 minute each)

17:15 - 19:00

Poster session 1 (odd numbers)

19:00 - 21:00

Dinner in the EMBL Canteen

21:00 - 23:00

After Dinner Drinks in the Rooftop Lounge

Day 2 - Friday 8 March 2019
TimeSpeaker
09:00 - 12:00
Session 2 - Structural Proteomics
Chair: Wade Harper - Harvard Medical School, USA
09:00 - 09:30

Rapid Investigation of Overproduced Proteins in Crude Samples
Michal Sharon - Weizmann Institute, Israel

09:30 - 10:00

Structural proteomics of protein complexes
Martin Beck - EMBL Heidelberg, Germany

10:00 - 10:45

Coffee Break and Meet the Speakers: Wade Harper, Michal Sharon, Martin Beck

10:45 - 11:15

The proteome in 3D
Paola Picotti - ETH Zurich, Switzerland

11:15 - 11:30

Enumerating the site occupancy, complexity, and diversity of mucin type O glycosylation on CD43 using electron transfer dissociation (ETD) mass spectrometry
Vandita Dwivedi - National Institute of Immunology, India

11:30 - 11:45

Cell Cycle Dependent Localization of Protocadherins
Nazli Ezgi Özkan Küçük - Koç University, Turkey

11:45 - 12:00

Multilayered proteomic interaction analysis identifies cancer mutations that affect the composition and function of kinase complexes
Martin Mehnert - ETH Zürich, Switzerland

12:00 - 13:30

Lunch

13:30 - 16:30

Session 3: Proteomics from lab to clinic
Chair: Vishva Dixit Genentech, USA

13:30 - 14:00

Microscaled methods for proteogenomic analysis of patient-derived tumors
Steven Carr - Broad Institute, USA

14:00 - 14:30

Peroxisome remodeling en route to virus replication
Ileana Cristea - Princeton University, USA

14:30 - 15:00

Novel MS scan modes applied to translational research
Matthias Mann - Max Planck Institute of Biochemistry, Germany

15:00 - 15:30

Coffee Break and Meet the Speakers: Steven Carr, Natalie Ahn, Paola Picotti

15:30 - 15:45

Using Tandem Mass Tag Proteomics for the Detection of Changes in Phosphorylation State After Treatment with a Tyrosine Kinase Inhibitor, Dasatinib
David Galbraith - Bristol Myers Squibb, United States of America

15:45 - 16:00

Plasma proteome profiling to detect and avoid sample related biases in biomarker studies
Philipp Geyer - Max Planck Institute of Biochemistry, Germany

16:00 - 16:15

Deep Phosphoproteomics Profiling of 20 Breast Cancer Cell Lines Reveals Distinct Molecular Signaling of Triple negative Breast Cancer
Alexander Hogrebe - University of Copenhagen, Denmark

16:15 - 16:30

Opposing effects of cancer type specific SPOP mutants
Namrata Udeshi - Broad Institute of MIT and Harvard, United States of America

16:30 - 17:15

Flash talks (even numbers - 1 slide / 1 minute each)

17:15 - 19:00

Poster session 2 (even numbers)

19:00 - 21:00

Conference Dinner in the EMBL canteen

21:00 - 00:00 Conference Party in the ATC Rooftop Lounge
Day 3 - Saturday 9 March 2019
TimeSpeaker
09:00 - 12:15
Session 4 - Cell signalling
Chair: Steven Carr - Broad Institute, USA
09:00 - 09:30 Measurements of protein motions by proteomics: The allosteric activation of ERK2 by phosphorylation
Natalie Ahn - University of Colorado, Boulder, USA
09:30 - 10:00

Unconventional Serine Ubiquitination: finding substrates, ligases and deubiquitinases
Ivan Dikic - Goethe University Frankfurt, Germany

10:00 - 10:30

New technologies to interrogate the dynamics and function of the phosphoproteome
Judit Villen - University of Washington, USA

10:30 - 11:00 Coffee break and Meet the Speakers: Ivan Dikic, Angus Lamond, Brenda Schulman
11:00 - 11:15

Deep proteome profiling of breast cancer cells unraveled subtype specific pathway dysregulations
Asfa Alli Shaik - Institute of Molecular and Cell Biology, Singapore

11:15 - 11:30

Proteome wide profiling of lysine deacetylase complexes with chemical probes
Iris Finkemeier - University of Muenster, Germany

11:30 - 11:45

A Precise and Sensitive LRRK2 Kinase Activity Assay by Targeted LC MS/MS Analysis of its Substrate Phosphorylation Stoichiometry
Ozge Karayel - Max Planck Institute of Biochemistry, Germany

11:45 - 12:00

Targeting the evolution of persistent clones in Jak2 mutated neoplasms
Ashok Kumar Jayavelu - Max Planck Institute of Biochemistry, Germany

12:00 - 12:15

Mining and integration of multi species proteomics data with the Biological Knowledge Graph
Alberto Santos - University of Copenhagen, Denmark

12:15 - 13:30 Lunch
13:30 - 14:30
Session 5 - Integrated Proteomics
Chair: Judit Villen - University of Washington, United States of America
13:30 - 14:00

Deep Proteomes, iPS cells & Data Mountains
Angus Lamond - University of Dundee, UK

14:00 - 14:30

Functional relevance of eukaryotic protein phosphorylation
Pedro Beltrao - EMBL-EBI, UK

14:30 - 14:40

Poster Prize

14:40 - 15:25

Keynote Speaker
Integrative studies of Ubiquitin Signaling
Brenda Schulman  - Max Planck Institute of Biochemistry, Germany

15:25 - 15:30

Closing Remarks

15:45

Departure