
Course Overview
The Synthetic Biology (SynBio) field has boomed in the last year, making it virtually impossible to cover every aspect of the field in one practical course. This course will focus on exploiting tools and concepts of SynBio for multi-scale engineering of bacterial systems.
Audience
The course is directed to PhD students and early post-doctoral researchers active in the areas of Molecular Microbiology, Bacterial Biotechnology, Systems Biology and Bioengineering.
Modules/Resources
The program consists of practicals with two daily lectures on some of the hottest topics in Bacterial SynBio, including:
[i] Genome engineering (incl. CRISPR and MAGE)
[ii] Customizing synthetic sRNAs as tools to control gene expression
[iii] Engineering of synthetic C1-metabolism
[iv] In vitro gene expression implementation
[v] Frugal screening of large biocatalyst libraries.
All students will engage in the corresponding activities. The practicals will focus on bacteria, while the lectures will encompass a suite of topics in contemporary Synthetic Biology.
Learning Outcomes
The participants will learn about the design and workflow of Synthetic Biology studies and gain understanding about the possibilities and limitations of Synthetic Biology in different areas.
The related EMBO Workshop: Creating is Understanding: Synthetic Biology Masters Complexity will take place 22 - 25 Sep 2019