Translational control is a major focus of attention that extends to many fields, including developmental biology, neurobiology, cell physiology, disease, synthetic and systems biology, among others. In addition to messenger RNA translation, the conference will feature advances in the fields of epitranscriptomics and non-coding RNAs that influence the translation process. Data-rich high-throughput technologies and structural advances will also be central, as they are pushing the field forward in manners that were unthinkable only few years ago, and are helping to create a “systems” view of translation.
With the increasing appreciation of the integration between different steps of gene expression, the conference will explore the connections between translation, mRNA turnover, nonsense-mediated decay, RNA localisation, splicing, etc. Finally, many alternatives to the classical “one message makes one protein” concept are being unraveled which increase the potential for regulation. These alternatives will be featured, as well as the role of translational regulation in diseases as diverse as cancer, neurological disorders or infectious diseases.
- Translation initiation
- Ribosome, elongation, termination
- Metabolism and disease
- RNP complexes
- Interconnections and turnover
- Methods and systems approaches
This conference is partnered with Cold Spring Harbor Laboratory (CSHL).