Location & dates EMBL Heidelberg, Germany 15 - 17 Dec 2020 Register interest
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organiser_miltenyi

Coronavirus information for participants

The onsite course and conference programme at EMBL has been paused until the end of June 2020.


We aim to continue offering our advanced training for the scientific community however we safely can. While some events have been cancelled, many have been rescheduled for a later date and others will be delivered as virtual events.


Registration is open for onsite courses and conferences starting after 1 July and for the virtual events. All registration fees for any events which don’t take place due to the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Registration is not yet open for this event. If you are interested in receiving more information please register your interest. 

Course Overview

Advances in cell and gene therapies (CGT) offer potential to transform medicine. Since the approval of the first two chimeric antigen receptor T cells (CAR-T) based therapies by the regulatory authorities in 2017, CAR-T have become one of the most promising personalized medicine in cancer treatment. 

More than two decades after the first engineered T cells created in the laboratory, we have come to grasp the fact that each patient requires not only personalised treatment but also a unique manufacturing process to ensure that the right CAR-T cell arrives at the patient bed. From good science to manufacturing know-how, every step in between is critical and requires extensive knowledge in both basic and applied sciences. To name a few, T cell biology, gene delivery technologies, target identification, CAR design, facilities setup, manufacturing process development, process control, release criteria, etc., all aspects must come together, before a patient could be benefited from the scientific breakthrough. 

This course, organized by Miltenyi Biotec and EMBL, will provide an unique overview, that participants will understand the vivid connections between basic science, cell manufacturing technologies and patient lives. The course aims to deliver an interactive repetition of the bench to bedside process — a unique and exciting course setting for basic and applied researchers in immunology and medicine.

Audience

Scientists in basic and medical research with a background in cellular and gene therapy who intend to initiate clinical applications in the near future; scientist with experience in stem cell transplantation who intend to work on advanced cell therapy manufacturing, and anyone intend to establish point-of-care CAR-T manufacturing. 

Modules/Resources

Scientific Session

  • CAR-T cells as a tool — what has it taken to get it to the bedside
  • Creating a patient specific CAR-T cell in R&D

Clinical Session

  • A review — the current state of effectiveness of CAR-T cells.

Manufacturing Session

  • Facilities setup and design
  • Manufacturing & process control
  • Quality control & in process control: How to assess safety of CAR-T cells prior to manufacturing and injection
  • Released criteria

Learning Outcomes

  • To understand challenges in translating pre-clinical work to patient use — caveats and pitfalls. 
  • To understand the importance of CAR-T product quality and safety — a very different approach is needed when moving away from academic in vitro research

EMBL Courses and Conferences are kindly supported by our Corporate Partnership Programme

Founder partners

  • Leica logo
  • Olympus logo

Corporate partners

  • 10x Genomics_120x82
  • Becton Dickinson logo
  • Bio-Rad logo
  • Boehringer Ingelheim logo
  • Eppendorf logo
  • GSK logo
  • Milteniy Biotec logo
  • Stilla logo
  • ThermoFisher logo

Associate partners

  • Merck logo
  • New England Biolabs logo
  • Nikon logo
  • Promega logo
  • Roche logo
  • Sanofi logo
  • Sartorius logo