Programme
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Time | Speaker | |
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11:00-13:00 | Registration and Lunch | |
13:00-13:30 | Opening talk The challenge of expanding the druggable proteome Adrian Carter, Boehringer Ingelheim, Germany |
|
13:30-15:30 |
Session 1: Illuminating the challenge and highlighting the opportunity for creating new medicines |
|
13:30-14:00 |
Illuminating the Druggable Genome with Informatics, Data Science and Machine Learning |
|
14:00-14:30 |
Heiko Runz - Biogen, USA |
|
14:30-15:00 |
Chemical probes and the chemical biology of cancer |
|
15:00-15:30 |
The challenges of creating new medicines: Joining forces to discover novel biological tools and apply new therapeutic modalities |
|
15:30-16:00 |
Coffee break |
|
16:00-18:15 |
Session 2: Illuminating the most promising proteins by virtue of druggability, human genetics and bioinformatics |
|
16:00-16:30 |
Eytan Ruppin - National Cancer Institute, USA |
|
16:30-16:45 |
Selected short talk |
|
16:45-17:15 |
Kristin Brown - GlaxoSmithKline, UK |
|
17:15-17:45 |
Judith Zaugg - EMBL Heidelberg, Germany |
|
17:45-18:15 |
Extending the small molecule similarity principle to all levels of biology |
|
18:15-19:30 |
Poster Session with beer and snacks |
|
19:30-20:30 |
Dinner |
|
20:30-22:00 | After Dinner Drinks ATC Rooftop Lounge |
Time | Speaker | |
---|---|---|
09:00-10:30 |
Session 3: Interrogating the druggable proteome with chemical probes, imaging and sensor proteins, part 1 |
|
09:00-09:30 |
Giulio Superti-Furga - Center for Molecular Medicine, Austria |
|
09:30-09:45 |
Selected short talk |
|
09:45-10:00 |
Selected short talk |
|
10:00-10:30 |
Stefan Knapp - Goethe University Frankfurt, Germany |
|
10:30-11:00 |
Coffee break |
|
11:00-11:30 |
Anne-Claude Gavin - University of Geneva, Switzerland |
|
11:30-11:45 |
Selected short talk |
|
11:45-12:00 | Selected short talk | |
12:00-12:30 |
Innate DNA sensing mechanisms in health and disease |
|
12:30-14:00 |
Meet the speakers and lunch |
|
14:00-16:00 |
Session 4: Interrogating the druggable proteome with chemical probes, imaging and sensor proteins, part 2 |
|
14:00-14:30 |
Kai Johnsson - Max Planck Institute for Medical Research, Germany |
|
14:30-15:00 |
Chemical physiology of natural products and antibody conjugates |
|
15:00-15:30 |
Training native electrophiles for covalent drug development |
|
15:30-16:00 |
Understanding cellular phenotypes; from screens to probes towards clinical candidates |
|
16:00-16:30 |
Coffee break |
|
16:30-19:00 | Session 5: Interrogating the druggable proteome with phenotypic screens Chair: Herbert Waldmann - Max Planck Institute of Molecular Physiology, Germany |
|
16:30-16:45 | Selected short talk | |
16:45-17:00 | Selected short talk | |
17:00-17:30 | Pseudo Natural Products Herbert Waldmann - Max Planck Institute of Molecular Physiology, Germany |
|
17:30-18:00 |
A systems approach to functional precision medicine by deep learning and multi-OMICs |
|
18:00-18:30 | Advances in phenotypic and pathway profiling: Elucidating novel target biology and drug mechanism-of-action under appropriate biological context Neil Carragher - The University of Edinburgh, UK |
|
18:30-19:00 | Michael Boutros - German Cancer Research Centre, Germany | |
19:00-20:30 | Dinner | |
20:30-23:00 | After Dinner Drinks, live music ATC Rooftop Lounge |
Time | Speaker |
---|---|
09:00-10:30 | Session 6: New engineering approaches for expanding the druggable proteome Chair: Stefan Knapp, Goethe University Frankfurt, Germany |
09:00-09:30 | Brenda Andrews - University of Toronto, Canada |
09:30-10:00 |
Biophysical screening of combinatorial libraries to target protein-protein interactions with covalent agents |
10:00-10:15 |
Selected short talk |
10:15-10:45 |
Christine Donahue - GlaxoSmithKline, USA |
10:45-11:15 |
Coffee break |
11:15-12:45 |
Session 7: New engineering approaches for breaking the druggability barrier |
11:15-11:45 |
Targeting the active site of E3 ligases with chemical tools |
11:45-12:15 |
Structure based PROTAC design to expand the druggable Proteome |
12:15-12:45 |
Chemical probes in target discovery |
12:45-13:15 |
Identification of microbiome-encoded enzymes involved in drug metabolism |
13:15-13:30 | Closing remarks |
13:30-14:00 |
End of conference |