Location & dates Virtual 23 - 31 Aug 2020 Register Now
Deadlines Registration - 30 Jun 2020
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EMBL Courses and Conferences during the Coronavirus pandemic

With the onsite programme paused, many of our events are now being offered in virtual formats.


Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.


More information for participants of events at EMBL Heidelberg can be found here.

Course Overview

Cryo-electron microscopy (cryo-EM) combined with image processing is currently undergoing what has been referred to as a “resolution revolution”, making it one of the most powerful techniques to address 3D molecular structure determination. It also has unique capabilities to obtain structural information in situ within complex environments, and to deal with heterogeneous samples. The methods are complex and under constant development, so in depth, advanced training of users is essential to ensure future users can adapt new technologies to expand into new areas and solve new biological problems. This course provides the theoretical and practical training covering the full cryo-EM breadth of techniques in order develop novel structure determination approaches.

Audience

The course is aimed at PhD students and PostDocs who already have some experience in cryo-EM and image processing, and who wish to learn the theory of cryo-EM image processing and more advanced practice with the aim of developing these techniques.

Modules/Resources

  • Single particle reconstruction (cisTEM, Relion, SPHIRE, cryoSPARCS)
  • Subtomogram averaging (Dynamo)
  • Single particle helical reconstruction (Spring)
  • Atomic model interpretation (Phenix, Refmac and Chimera)
  • EM databank

Learning Outcomes

After this course, students should have learned advanced topics of cryo-EM data collection and image processing and be able to apply and adapt these techniques for challenging research projects.

EMBL Courses and Conferences are kindly supported by our Corporate Partnership Programme

Founder partners

  • Leica logo
  • Olympus logo

Corporate partners

  • 10x Genomics_120x82
  • Becton Dickinson logo
  • Bio-Rad logo
  • Boehringer Ingelheim logo
  • Eppendorf logo
  • GSK logo
  • Milteniy Biotec logo
  • NetApp logo
  • Stilla logo
  • ThermoFisher logo

Associate partners

  • Merck logo
  • New England Biolabs logo
  • Nikon logo
  • Promega logo
  • Roche logo
  • Sanofi logo
  • Sartorius logo