EMBL Courses and Conferences during the Coronavirus pandemic
With the onsite programme paused, many of our events are now being offered in virtual formats.
Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.
More information for participants of events at EMBL Heidelberg can be found here.
Programme
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| Time | Speaker | |
|---|---|---|
| 08:00-09:30 | Registration | |
| Session 1: RNA modification I (m6A) Chair: TBA |
||
| 09:30-09:45 | Opening remarks | |
| 09:45-10:45 |
Keynote Lecture: RNA methylation in gene expression regulation |
|
| 10:45-11:15 |
Reading and writing epitranscriptomic modifications at mRNA caps and at internal sites |
|
| 11:15-11:30 |
Mettl3/Mettl14 inhibitors and YTHDF antagonists: when and why to go biophysical with your target Gerhard Müller - Gotham Therapeutics GmbH, Germany |
|
| 11:30-12:00 |
Gene regulation by RNA modifications Ramesh Pillai - University of Geneva, Switzerland |
|
| 12:00-13:30 |
Meet the speakers and Lunch |
|
| 13:30-13:45 |
The role of YTHDF readers in maternal transcript clearance and embryonic development Cassandra Kontur - Yale University, USA |
|
| 13:45-14:00 |
NOseq today: fractional occupancy of m6A sites Mark Helm - Johannes Gutenberg-University, Germany |
|
| 14:00-14:15 |
Nanopore direct RNA sequencing identifies interactions between RNA methylation and poly(A) site choice Matthew Parker - The University of Dundee, UK |
|
| 14:15-14:30 |
m6ACE-seq as a tool to identify and characterize RNA methylation writers and erasers Sho Goh - Genome Institute of Singapore, Singapore |
|
| 14:30-14:45 |
METTL3-mediated m6A modifications control antibody immune responses Amalie Grenov - The Weizmann Institute of Science, Israel |
|
| 14:45-15:15 |
Coffee Break |
|
|
Session 2: RNA modifications in stem cells and development |
||
| 15:15-15:45 |
Role of RNA methylation in gene regulation and cancer |
|
| 15:45-16:15 |
RNA pseudouridylation in development and tumorigenesis Cristian Bellodi - Lund University, Sweden |
|
| 16:15-16:30 |
Ythdf readers compensate each other in a context specific manner Noa Novershtern - The Weizmann Institute of Science, Israel |
|
| 16:30-17:00 |
Tell-Tale Poly(A) Tails |
|
| 17:00-19:00 |
Poster Session I with beer and snacks |
|
| 19:00-21:00 |
Dinner |
|
| 21:00-23:00 | Welcome reception with live jazz duo | |
| Time | Speaker | |
|---|---|---|
| Session 2 (cont.) - RNA modifications in stem cells and development Chair: TBA |
||
| 09:00-09:30 |
Cross-evolutionary analysis of RNA acetylation from single nucleotide to near-atomic resolution |
|
| 09:30-09:45 |
Control of cellular proliferation in plant organogenesis by an m6A-YTHDF module Laura Arribas-Hernández - University of Copenhagen, Denmark |
|
|
Session 3: RNA modification II (m5C, m1A, 3’ terminal additions, etc) |
||
| 09:45-10:15 |
Effects of RNA modifications on RNA structure |
|
| 10:15-10:30 |
No evidence for N7-methylation of guanosine (m7G) in human miRNAs Vinther Jeppe - University of Copenhagen, Denmark |
|
| 10:30-11:00 | Coffee break | |
| 11:00-11:30 |
Structure and Function of RNA m6A methyltransferases |
|
| 11:30-11:45 |
m5C Modification of an Epstein-Barr Virus Noncoding RNA Decreases its Stability Nara Lee - University of Pittsburgh, USA |
|
| 11:45-12:00 |
Molecular Characterization of Uridylation-mediated RNA Decay by the Drosophila TRUMP Complex Annamaria Sgromo - Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Austria |
|
| 12:00-13:30 |
Meet the Speakers and Lunch |
|
| 13:30-14:00 |
Acetylation of cytidine in messenger RNA regulates translation Shalini Oberdoerffer - National Cancer Institute, USA |
|
| 14:00-14:15 |
Molecular connection between the TUTase URT1 and decapping activators Dominique Gagliardi - IBMP-CNRS-University of Strasbourg, France |
|
| 14:15-14:45 |
The molecular mechanisms and interactome of human adenosine demethylases |
|
| 14:45-15:00 |
Noncanonical poly(A) polymerase TENT5C regulates B cell humoral response and differentiation Seweryn Mroczek - Warsaw University, Poland |
|
| 15:00-15:30 | Coffee break | |
| Session 4 - RNA modification pathways in physiology and pathology Chair: TBA |
||
| 15:30-16:00 | Targeting RNA modifications to eliminate cancer stem cells in acute myeloid leukaemia Kamil Kranc - Barts Cancer Institute, Queen Mary University of London, UK |
|
| 16:00-16:15 |
Targeting cancer with first-in-class inhibitors of the RNA m6A writer METTL3 Alexandra Sapetschnig - Storm Therapeutics, UK |
|
| 16:15-16:45 |
Modifications of RNA: Their function and role in cancer |
|
| 16:45-17:00 |
The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and fecundity in Caenorhabditis elegans Markus Schosserer - University of Natural Resources and Life Sciences, Austria |
|
| 17:00-19:00 |
Poster Session II |
|
| 19:00-21:00 |
Dinner in the EMBL Canteen |
|
| 21:00-24:00 | Party in the Roof Top Lounge | |
| Time | Speaker |
|---|---|
| Session 4 (cont.) - RNA modification pathways in physiology and pathology Chair: TBA |
|
| 09:00-09:30 | mRNA cap regulation in cell fate decisions Victoria Cowling - University of Dundee, UK |
| 09:30-09:45 |
Escaping the plant cell: m5C RNA methylation and tRNA-like structures as signals for long-distance mRNA mobility in Arabidopsis Eleftheria Saplaoura - Max Planck Institute of Molecular Plant Physiology, Germany |
| 09:45-10:00 |
The ribosomal RNA modification code at single nucleotide resolution Eva Maria Novoa - Centre for Genomic Regulation, Spain |
| Session 5 - Emerging concepts Chair: TBA |
|
| 10:00-10:30 |
tRNA m5C in cancer biology |
| 10:30-10:45 |
Dinucleoside polyphosphates act as 5' RNA caps in bacteria Hana Cahova - Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic |
| 10:45-11:15 |
Coffee break |
| 11:15-11:45 |
Regulating mammalian gene expression by RNA pseudouridylation |
| 11:45-12:00 |
Thiolation: not only a tRNA business Riccardo Pecori - German Cancer Research Center, Germany |
| 12:00-12:30 |
Making RNA demethylation visible with NAIL-MS |
| 12:30-12:45 |
Terminal nucleoitde additions and mRNA decay |
| 12:45-13:15 |
Closing Remarks |
| 13:15-13:30 |
Packed Lunch Bus downtown and Frankfurt Airport (airport shuttle tickets for sale at registration desk) |