EMBL Courses and Conferences during the Coronavirus pandemic
With the onsite programme paused, many of our events are now being offered in virtual formats.
Registration is open as usual for many events, with back-up plans in place to move further courses and conferences online as necessary. Registration fees for any events affected by the COVID-19 disruption are fully refundable.
More information for participants of events at EMBL Heidelberg can be found here.
Registration is not yet open for this event. If you are interested in receiving more information please register your interest.
Course Overview
Circular RNAs (CircRNAs) are a rediscovered class of RNA species that originate from back-splicing events, which have been reported across all domains of life. Many circular RNAs are stable, abundant and conserved between species. They exhibit context-dependent expression patterns, which are often linked to disease states. Validated circular RNA functions are numerous and range from regulation of transcription and splicing to RNA/protein sponging and scaffolding. However, CircRNAs are by and large the most underexplored class of all non-coding RNAs. This course will meet the specific need to explore complexity, distribution, function and mechanisms of circRNA action experimentally and computationally.
The presented methods and approaches are widely applicable to all organisms beyond standard models. Lectures will cover the technological background of circular RNA research and present the latest advancements from biology, chemistry and medicine. The practical part will include detection and quantification of circRNAs by low- and high-throughput methods, data analysis and integration as well as comprehensive computational assessment of circRNA candidates, function prediction and experimental design of follow-up experiments.
Audience
This course is intended for PhD students and young Postdoctoral researchers.
Modules/Resources
- RNA splicing
- Computational biology
- Gene expression
- RNA localisation
- Quantitative biology
Learning Outcomes
Participants will go through all wet-lab steps required for preparation of circRNA-seq libraries and will be introduced to basic bioinformatics required for analyses of circRNA-seq data.
What past participants say about the course:
"Such an excellent atmosphere, brilliant speakers and amazing facilities. I have learnt so much and have been inspired for my future work. I would highly recommend EMBL courses to anyone who is passionate about science." - Anya Arthurs, Flinders University, Australia
"This was the most interesting course I have ever attended! Great renown speakers, very motivated participants and a perfect organization!" - Steffen Fuchs, Charité – Universitätsmedizin Berlin, Germany
